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TranscriptomicsDox-regulated Notch4 overexpression in mouse ES cells redirects hemagioblasts to a cardiac fate.
Previous studies have demonstrated that distinct progenitor subpopulations of mesoderm display tissue specific and vascular potential: hemangioblasts, a progenitor population capable of generating cells of the hematopoietic, endothelial and vascular smooth muscle lineages, and a multipotential proge...
ORGANISM(S): Mus musculus 
2010-09-15 | E-GEOD-12425 | biostudies-arrayexpress
GenomicsMus musculus
The C-terminal multimerization domain is essential for leukemia development by CBFβ-SMMHC
PRJNA390612 | ENA
GenomicsGata2 deficiency delays leukemogenesis while contributes to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice
Gata2 deficiency delays leukemogenesis while contributes to aggressive leukemia phenotype in Cbfb-MYH11 knockin mice
PRJNA535600 | ENA
GenomicsMus musculus
CHD7 deficiency delays leukemogenesis in mice induced by CBFB-MYH11
PRJNA397602 | ENA
UnknownDistinct circulating cytokine/chemokine profiles correlate with clinical benefit of immune checkpoint inhibitor monotherapy and combination therapy in advanced non-small cell lung cancer.
Not available
S-EPMC10278479 | biostudies-literature
UnknownEukaryotic Initiation Factor 5A2 localizes to actively translating ribosomes to promote cancer cell protrusions and invasive capacity.
Not available
S-EPMC10009989 | biostudies-literature
ProteomicsHigh-dose oncogenic PIK3CA drives constitutive cellular stemness through increased NODAL/TGFb signaling
Oncogenic PIK3CA mutations activate phosphoinositide 3-kinase (PI3K) and are among the commonest somatic mutations in cancer and mosaic, developmental overgrowth disorders. We recently demonstrated that the ‘hotspot’ variant PIK3CAH1047R exerts striking allele dose-dependent effects on stemness in h...
ORGANISM(S): Homo sapiens (Human) 
2021-03-03 | PXD014719 | Pride
Proteomics Tfgb Nodal ipsc Cancer Transcriptomics Pik3ca 
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