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GenomicsAcerihabitans sp. TG2
Acerihabitans sp. TG2 Genome sequencing and assembly
PRJNA1041642 | ENA
TranscriptomicsTranscriptomic analysis of mouse splenic B cells that are either TG2-sufficient or TG2-deficient
To compare the transcriptomes of TG2-sufficient and TG2-deficient mouse splenic B cells under resting and stimulated conditions.
ORGANISM(S): Mus musculus 
2019-11-08 | E-MTAB-7567 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of ATRA-differentiated wild-type and TG2 knockout NB4 cells
Treatment of acute promyelocytic leukemia (APL) with all-trans-retinoic acid (ATRA) results in terminal differentiation of leukemic cells toward neutrophil granulocytes. Administration of ATRA leads to massive changes in gene expression, including down-regulation of cell proliferation-related genes ...
ORGANISM(S): Homo sapiens 
2010-12-01 | E-GEOD-23702 | biostudies-arrayexpress
ProteomicsComprehensive detection of isopeptides between human tissue transglutaminase and gluten peptides using a reciprocal proteomic approach
Celiac disease (CD) is a chronic inflammation of the small intestine triggered by the ingestion of gluten in genetically predisposed individuals. Tissue transglutaminase (TG2) is a key factor in the pathogenesis of CD, because it catalyzes both the deamidation of specific glutamine residues and the ...
ORGANISM(S): Homo sapiens (Human) Triticum aestivum (Wheat) 
2019-09-27 | PXD014067 | Pride
Celiac disease  transglutaminase  isopeptides  gluten 
GenomicsTranscriptomic analysis of mouse splenic B cells that are either TG2-sufficient or TG2-deficient
Transcriptomic analysis of mouse splenic B cells that are either TG2-sufficient or TG2-deficient
PRJEB35258 | ENA
ProteomicsThe Transglutaminase-2 interactome in the APP23 mouse model of Alzheimer disease
Amyloid-beta (Aβ) deposition in the brain, is closely linked to development of Alzheimer’s disease (AD). Unfortunately, therapies specifically targeting Aβ deposition have failed to reach their primary clinical endpoints, emphasizing the need to broaden the search strategy for identification of alt...
ORGANISM(S): Mus musculus (Mouse) 
2022-02-22 | PXD030354 | Pride
Lc-msms swath mouse tgm2 alzheimer's 
ProteomicsProteomic profiling in mouse kidneys post-UUO
Increased export of transglutaminase-2 (TG2) by tubular epithelial cells (TECs) into the surrounding interstitium modifies the extracellular homeostatic balance leading to fibrotic membrane expansion. Although silencing of extracellular TG2 ameliorates progressive kidney scarring in animal models of...
ORGANISM(S): Mus musculus (Mouse) 
2018-02-07 | PXD008173 | Pride
Swath Transglutaminase-2 Mouse Chronic kidney disease 6600 Kidney 
GenomicsThe transcriptional role of TG2-mediated H3Q5ser in CRC [RNA-seq]
The transcriptional role of TG2-mediated H3Q5ser in CRC [RNA-seq]
PRJNA956440 | ENA
GenomicsThe transcriptional role of TG2-mediated H3Q5ser in CRC [ChIP-seq]
The transcriptional role of TG2-mediated H3Q5ser in CRC [ChIP-seq]
PRJNA956437 | ENA
TranscriptomicsGene expression profiling of ATRA-differentiated wild-type and TG2 knockout NB4 cells
Treatment of acute promyelocytic leukemia (APL) with all-trans-retinoic acid (ATRA) results in terminal differentiation of leukemic cells toward neutrophil granulocytes. Administration of ATRA leads to massive changes in gene expression, including down-regulation of cell proliferation-related genes ...
ORGANISM(S): Homo sapiens 
2010-12-01 | GSE23702 | GEO
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