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ProteomicsMapping of transglutaminase 2 active sites of human salivary small basic proline-rich
Due to the distinctive features of oral mucosa, determination of the proteins involved in the formation of “oral protein pellicle” is demanding. The present study investigated the susceptibility of several human basic proline-rich peptides (bPRPs) named P-H, P-D, P-F, P-J, and II-2 as substrates of ...
ORGANISM(S): Homo sapiens (Human) 
2019-10-25 | PXD014658 | Pride
Bprps Saliva Transglutaminase 2 Human 
TranscriptomicsTranscription profiling of sputum samples from individuals exercise-induced bronchoconstriction (EIB).
Asthma is a heterogeneous disease. Exercise-induced bronchoconstriction (EIB) is a distinct syndrome that occurs in 30-50% of asthmatics and is characterized by high levels of pro-inflammatory eicosanoids. We identified genes differentially expressed in the airways of asthmatics with EIB relative to...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-13785 | biostudies-arrayexpress
ProteomicsInfection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis
Transglutaminase 2 (TG2) is a ubiquitous enzyme with transamidating activity. We report here that the expression and activity of TG2 are enhanced in cells infected with the obligate intracellular bacteria Chlamydia trachomatis. Genetic or pharmacological inhibition of TG2 activity impair bacterial d...
ORGANISM(S): Homo sapiens (Human) Chlamydia trachomatis E/C599 
2020-02-25 | PXD017117 | Pride
Chlamydia Hexosamine biosynthesis O-glcnacylation Gfpt Transglutaminase 2 
TranscriptomicsRole of Transglutaminase 2 in Liver Injury via Crosslinking and Silencing of Transcription Factor, Sp1
Gene expression of Ethanol-treated hepatocytes from WT and transglutaminase 2 knockout mice Keywords: transglutmianse 2
ORGANISM(S): Mus musculus 
2009-02-24 | GSE10285 | GEO
ProteomicsTissue Transglutaminase 2 has higher affinity for relaxed than for stretched fibronectin fibers
Chemical cross-linking coupled to mass spectrometry was used to study the interaction between fibronectin (Fn; full-length or gelatin-binding domain fragment = Fn 45) with tissue transglutaminase 2 in oxidized and non-oxidized form. The complexes were cross-linked with disuccinimidyl suberate (DSS) ...
ORGANISM(S): Homo sapiens (Human) 
2023-12-20 | PXD043976 | Pride
Chemical cross-linking  dss  pdh  dmtmm  structural proteomics  fibronectin Tissue transglutaminase 2 
GenomicsTransglutaminase 2 regulates vimentin-dependent proteostasis during macrophage activation in sepsis
Transglutaminase 2 regulates vimentin-dependent proteostasis during macrophage activation in sepsis
PRJNA1284302 | ENA
GenomicsEssential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation.
Essential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation.
PRJNA635413 | ENA
GenomicsEssential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation.
Essential role for CD30-Transglutaminase 2 axis in memory Th1 and Th17 cell generation.
PRJNA636972 | ENA
GenomicsTransglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment
Transglutaminase 2 regulates ovarian cancer metastasis by modulating the immune microenvironment
PRJNA1293375 | ENA
TranscriptomicsTranscription profiling of mouse ethanol-treated hepatocytes from WT and transglutaminase 2 knockouts reveals role of transglutaminase 2 in liver injury via crosslinking and silencing of transcription factor, Sp1
Gene expression of Ethanol-treated hepatocytes from WT and transglutaminase 2 knockout mice Experiment Overall Design: Non or 100mM Ethanol-treated WT hepatocytes, Non or 100mM Ethanol-treated TG2KO hepatocytes. Experiment Overall Design: 8 of Samples were analysed (its replicates are included)
ORGANISM(S): Mus musculus 
2009-02-28 | E-GEOD-10285 | biostudies-arrayexpress
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