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ProteomicsImmunomodulation of T helper cells by tumour microenvironment in oral cancer is associated with rapid membrane-associated Vitamin D signalling pathway
The immune system plays a key role in the protective response against oral cancer, however the tumour microenvironment (TME) is able to impair this anti-cancer response by modulating T helper (Th) responses and promoting an anti-inflammatory environment. Regulatory T cells (Tregs) and Th2 effector c...
ORGANISM(S): Homo sapiens (Human) 
2021-04-29 | PXD023049 | Pride
Immunomodulation Ccr8 Th-like tregs Oral cancer Cancer immunology 
UnknownAn Atlas of Human Regulatory T Helper-like Cells Reveals Features of Th2-like Tregs that Support a Tumorigenic Environment.
Not available
S-EPMC5529316 | biostudies-literature
UnknownTregs from human blood differentiate into nonlymphoid tissue-resident effector cells upon TNFR2 costimulation.
Not available
S-EPMC10972588 | biostudies-literature
GenomicsLoss of Bcl3 influences gene expression in Tregs and Treg subsets [Bcl3-WT_Treg_bulkRNAseq]
Loss of Bcl3 influences gene expression in Tregs and Treg subsets [Bcl3-WT_Treg_bulkRNAseq]
PRJNA1008843 | ENA
UnknownMicroRNA-125a-5p regulates the effect of Tregs on Th1 and Th17 through targeting ETS-1/STAT3 in psoriasis.
Not available
S-EPMC10543306 | biostudies-literature
GenomicsNanostring gene expression analysis of Tregs islated from Kdr KO versus transgene control SB1 tumors
Nanostring gene expression analysis of Tregs islated from Kdr KO versus transgene control SB1 tumors
PRJNA1205776 | ENA
TranscriptomicsNanostring gene expression analysis of Tregs islated from Kdr KO versus transgene control SB1 tumors
Tumor-infiltrating Tregs were FACS sorted using their YFP signal from processed SB1 tumors implanted in Kdr(fl/fl)xFoxp3(yfp-cre) or Kdr(+/+)xFoxp3(yfp-cre) mice, fro which RNA was isolated for Nanostring analysis usig the Murine Cancer Immune Profiling Panel Anti-VEGF treatment has shown clinical a...
ORGANISM(S): Mus musculus 
2025-03-14 | GSE285761 | GEO
TranscriptomicsTargeted next generation sequencing of 589 genes identifies complementary responses in t-helper-like T regulatory cells
Regulatory T-cells (Tregs) play a pivotal role in maintaining peripheral immunological tolerance, by preventing autoimmunity and chronic inflammation. However, they can also play a parallel role in the promotion of antitumor responses. Tregs can be classified as T helper (Th)-like Tregs that phenoty...
ORGANISM(S): Homo sapiens 
2017-06-12 | GSE99733 | GEO
TranscriptomicsTranscriptomic analysis of human regulatory (Treg) and effector (Teff) CD4+ memory T cells in the presence of oral cancer secretome versus not malignant secretome
The immune system plays a key role in the protective response against oral cancer; however, the tumour microenvironment (TME) is able to impair this anti-cancer response by modulating T helper (Th) responses and promoting an anti-inflammatory environment. Regulatory T cells (Tregs) and Th2 effector ...
ORGANISM(S): Homo sapiens 
2021-04-08 | GSE171638 | GEO
UnknownTbet Expression in Regulatory T Cells Is Required to Initiate Th1-Mediated Colitis.
Not available
S-EPMC6749075 | biostudies-literature
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