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TranscriptomicsGATA3 acts upstream of FOXA1 in mediating ER binding by shaping enhancer accessibility
Estrogen Receptor (ESR1) drives growth in the majority of human breast cancers by binding to regulatory elements and inducing transcription events that promote tumor growth. Differences in enhancer occupancy by ESR1, contribute to the diverse expression profiles and clinical outcome observed in brea...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-39623 | biostudies-arrayexpress
ProteomicsPreliminary cell culture models for subclinical mastitis in sheep
Ovine mastitis is defined as the inflammation of the sheep udder, most commonly caused in response to intramammary infections. Based on the occurrence of clinical signs, mastitis is characterized as either clinical or subclinical (SCM). The impact of ovine SCM on the overall sustainability of dairy ...
ORGANISM(S): Ovis aries 
2022-11-03 | PXD036985 | Pride
Cell culture models Mastitis Secreted proteins Ovine In vitro infection 
UnknownCan We Barter Local Taxes for Maintaining Our Green? A Psychological Perspective.
Not available
S-EPMC8920541 | biostudies-literature
UnknownObjective greenness, connectedness to nature and sunlight levels towards perceived restorativeness in urban nature.
Not available
S-EPMC10598040 | biostudies-literature
GenomicsGenome-wide mapping of SPDEF and ESR1 binding in MCF-7 cells (ChIP-seq)
Using a transcriptional network derived from 2000 breast cancer gene expression profiles we identify the master regulators (MRs) of FGFR2 signalling. To validate the identified regulons, we examined whether there was enrichment of TF binding near the transcription start sites (TSS) of genes found in...
ORGANISM(S): Homo sapiens 
2013-07-17 | E-GEOD-48930 | biostudies-arrayexpress
ProteomicsProteome Changes Induced by Imatinib and Novel Imatinib Derivatives in K562 Human Chronic Myeloid Leukemia Cells
Inhibition of deregulated protein kinases by small molecule drugs has evolved into a major therapeutic strategy for the treatment of human malignancies. Imatinib mesylate has emerged as the leading compound to treat chronic myeloid leukemia (CML), through its inhibition of Bcr- Abl tyrosine kinases,...
ORGANISM(S): Homo sapiens (Human) 
2014-06-30 | PXD000216 | Pride
Human Lc-msms K562 Silac Long columns Imatinib 
UnknownSentence Repetition as a Tool for Screening Morphosyntactic Abilities of Bilectal Children with SLI.
Not available
S-EPMC5723908 | biostudies-literature
UnknownBibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021.
Not available
S-EPMC9705792 | biostudies-literature
UnknownPrimary Care Doctors' Assessment of and Preferences on Their Remuneration.
Not available
S-EPMC5798707 | biostudies-literature
UnknownRAN-related neural-congruency: a machine learning approach toward the study of the neural underpinnings of naming speed
Not available
S-EPMC10319123 | biostudies-literature
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