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ProteomicsAn Integrated Proteomic Portrait of Prostate Cancer Progression
Cancer forms a local tumor that subsequently metastasizes to distant organs. In prostate cancer, the latter part of the trajectory is influenced by the inhibition of the androgen receptor (AR). The study of proteomic changes along disease progression may reveal insights into how prostate cancer evol...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) Mus Musculus (ncbitaxon:10090) 
2024-10-30 | MSV000096252 | MassIVE
ProteomicsTargeting FOXA1 and FOXA2 Disrupts the Lineage-Specific Oncogenic Output in Prostate Cancer
Activation of the androgen receptor (AR) is the key lineage-specific oncogenic pathway and the primary therapeutic target in prostate cancer. While AR signaling is enabled by the pioneer transcription factor FOXA1, its homolog FOXA2 is specifically expressed in advanced lineage plasticity prostate c...
ORGANISM(S): Homo sapiens (Human) 
2026-01-27 | PXD057803 | Pride
Foxa1 Ar negative prostate cancer Foxa2 Targeting transcription factor Chromatin 
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