Sort   by:  
 Page size 
MetabolomicsFOXA2 controls the anti-oxidant response in FH-deficient cells independent of NRF2
Not available
ORGANISM(S): Mus musculus 
ST002199 | MetabolomicsWorkbench
TranscriptomicsIdentification of candidate FOXA2-regulated genes in the adult mouse uterus
To identify candidate genes regulated by forkhead transcription factor box A2 (FOXA2) in the uterus, control and Foxa2-deleted uteri were collected at day of pseudopregnancy (DOPP) 3.5 (DOPP 0.5= vaginal plug). Microarray analysis identified differentially expressed genes in the Foxa2-deleted as ...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-48339 | biostudies-arrayexpress
ProteomicsIdentify FOXA2-interacting proteins in NEPC cells
Following extensive treatment with androgen receptor (AR) pathway inhibitors, a significant number of metastatic prostate cancer develop treatment resistance, and approximately 20% of these castration-resistant prostate cancers (CRPC) transdifferentiate, at least partially, into neuroendocrine (NE) ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-12 | PXD061080 | Pride
Nepc Foxa2 
ProteomicsIdentify FOXA2-interacting proteins in NEPC cells
Following extensive treatment with androgen receptor (AR) pathway inhibitors, a significant number of metastatic prostate cancer develop treatment resistance, and approximately 20% of these castration-resistant prostate cancers (CRPC) transdifferentiate, at least partially, into neuroendocrine (NE) ...
ORGANISM(S): Homo sapiens (Human) 
2025-06-12 | PXD061127 | Pride
Nepc Foxa2 
GenomicsFOXA2 regulates a network of genes involved in critical functions of intestinal epithelia
Background and Aims: The forkhead box A (FOXA) family of pioneer transcription factors is critical for the development of many endoderm-derived tissues including the lung and the liver. Here we investigate the role of FOXA2 in regulating intestinal epithelial cell function. Methods: ChIP-seq was use...
ORGANISM(S): Homo sapiens 
2015-08-06 | E-GEOD-66218 | biostudies-arrayexpress
GenomicsChIP-seq analysis of Foxa2 binding sites in midbrain dopaminergic progenitors
Embryonic stem (ES) cells were differentiated in culture to midbrain dopaminergic (mDA) progenitors and subjected to ChIP-seq analysis to resolve genome-wide binding sites of forkhead box protein A2 (Foxa2). Foxa2 was found to directly regulate multiple lineage pathways to specify midbrain dopaminer...
ORGANISM(S): Mus musculus 
2012-07-01 | E-MTAB-1137 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of adult mouse liver to identify Foxa2 targets
We performed genome-wide location analysis for Foxa2 to identify its targets in the adult mouse liver. Chromatin isolated from the liver of five adult mice was cross-linked, sheared and immunoprecipitated with a Foxa2-specific antibody. The resulting material, as well as material that was not immu...
ORGANISM(S): Mus musculus 
2008-07-04 | E-MTAB-32 | biostudies-arrayexpress
TranscriptomicsChromatin immunoprecipitation of wild type and Foxa2 knock-out mouse liver using anti-HNF6 anitbodies to test whether Foxa2 inhibits HNF6-mediated transcription in the liver
The aim of this study was to test, in vivo, if Foxa2 inhibits HNF6-mediated transcription in the liver. We utilized hepatocyte-specific gene ablation of Foxa2 and the Mouse PromoterChip BCBC 3.0 and Mouse PancChip 5.0 cDNA microarrays to investigate HNF6 binding to its target promoters in vivo in t...
ORGANISM(S): Mus musculus 
2007-09-14 | E-CBIL-36 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of wild type and Foxa2 knock out mouse mature beta cells
The winged helix transcription factor Foxa2 regulates Pdx1 gene expression and fetal endocrine pancreas development. We show here by inducible gene ablation that Foxa2 inactivation in mature beta-cells induces hyperinsulinemic hypoglycemia in Foxa2loxP/loxP, Pdx1-CreERT2 adult mice. Mutant beta-cell...
ORGANISM(S): Mus musculus 
2007-09-22 | E-CBIL-39 | biostudies-arrayexpress
ProteomicsTargeting FOXA1 and FOXA2 Disrupts the Lineage-Specific Oncogenic Output in Prostate Cancer
Activation of the androgen receptor (AR) is the key lineage-specific oncogenic pathway and the primary therapeutic target in prostate cancer. While AR signaling is enabled by the pioneer transcription factor FOXA1, its homolog FOXA2 is specifically expressed in advanced lineage plasticity prostate c...
ORGANISM(S): Homo sapiens (Human) 
2026-01-27 | PXD057803 | Pride
Foxa1 Ar negative prostate cancer Foxa2 Targeting transcription factor Chromatin 
Sort   by:  
 Page size