Sort   by:  
 Page size 
TranscriptomicsRNAseq of FACS-sorted C.elegans neurons from wildtype and thoc-5(wy822) mutant animals.
We sorted approx. 10000 neurons per sample from day one adult worms. We collected two wildtype samples and three thoc-5(wy822) mutant samples.
ORGANISM(S): Caenorhabditis elegans 
2018-06-01 | GSE102300 | GEO
UnknownCDK11 in TREX/THOC Regulates HIV mRNA 3' End Processing.
Not available
S-EPMC4648707 | biostudies-literature
Genomics
WGS of C. elegans thoc-5 mutants
PRJNA678136 | ENA
ProteomicsHMGB1 interactome in prostate and ovarian cancer cells
This study reports the interactome of HMGB1 in prostate and ovarian cancer cells, which includes a variety of proteins involved in diverse cellular processes. Subcellular fractionation is used to map the distribution of interacting proteins. In the nucleus, HMGB1 interacts directly with NuRD complex...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD026258 | Pride
Septin Thoc complex Prostate cancer Ovarian cancer Ribosome biogenesis Hmgb1 Skov-1 Nurd complex Rab11 Pc3 
GenomicsCaenorhabditis elegans
RNAseq of FACS-sorted C.elegans neurons from wildtype and thoc-5(wy822) mutant animals.
PRJNA397415 | ENA
UnknownHMGB1 Protein Interactions in Prostate and Ovary Cancer Models Reveal Links to RNA Processing and Ribosome Biogenesis through NuRD, THOC and Septin Complexes.
Not available
S-EPMC8466577 | biostudies-literature
UnknownThe THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase+ cells and telomeric recombination in ALT+ cells.
Not available
S-EPMC10359610 | biostudies-literature
UnknownThe THO Complex Coordinates Transcripts for Synapse Development and Dopamine Neuron Survival.
Not available
S-EPMC6542560 | biostudies-literature
OtherYTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks
Certain environmental toxins are nucleic acid damaging agents, as are many chemotherapeutics used for cancer therapy. These agents induce various adducts in DNA as well as RNA. Indeed, most of the nucleic acid adducts (>90%) formed due to these chemicals, such as alkylating agents, occur in RNA. How...
ORGANISM(S): Homo sapiens 
2024-12-03 | GSE283317 | GEO
UnknownTHOC2 and THOC5 Regulate Stemness and Radioresistance in Triple-Negative Breast Cancer.
Not available
S-EPMC8693071 | biostudies-literature
Sort   by:  
 Page size