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TranscriptomicsNovel kinase fusion oncogenes in post-Chernobyl radiation-induced pediatric thyroid cancers
Exposure to ionizing radiation during childhood markedly increases the risk of developing papillary thyroid cancer. We identified non-overlapping somatic driver mutations in all 26 cases of post-Chernobyl thyroid cancers we studied through candidate gene assays and next generation RNA-sequencing. We...
ORGANISM(S): Homo sapiens 
2013-10-25 | E-GEOD-48850 | biostudies-arrayexpress
UnknownTherapeutic Impact of Cytoreductive Surgery and Irradiation of Posterior Fossa Ependymoma in the Molecular Era: A Retrospective Multicohort Analysis.
Not available
S-EPMC4962737 | biostudies-literature
ProteomicsProteomic analysis of clear cell renal cell carcinoma tissue versus matched normal kidney tissue
We analyzed 84 tumor/normal pairs (177 total) using standard shotgun proteomic techniques in order to characterize the molecular landscape of clear cell renal cell carcinoma (ccRCC) and interrogated changes in protein abundance and biological pathways with ccRCC grade. These tissues were distributed...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-20 | MSV000079972 | MassIVE
TranscriptomicsDeep sequencing analysis of the developing mouse brain reveals a novel microRNA
MicroRNAs (miRNAs) are small non-coding RNAs that can exert multilevel inhibition/repression at a post-transcriptional or protein synthesis level during disease or development. Characterisation of miRNAs in adult mammalian brains by deep sequencing has been reported previously. However, to date, no ...
ORGANISM(S): Mus musculus 
2011-04-04 | E-GEOD-22653 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of yeast transcription factor deletion strains perturbed with methyl-methanesulfonate
Gene expression profiles of transcription factor deletion strains (S.cerevisiae) perturbed with 0.03% methyl-methanesulfonate for 60 minutes
ORGANISM(S): Saccharomyces cerevisiae 
2006-05-19 | E-TABM-93 | biostudies-arrayexpress
GenomicsBase-pair resolution DNA methylation sequencing reveals profoundly divergent epigenetic landscapes in Acute Myeloid Leukemia
Here we used Illumina NGS for high-throughput profiling of the DNA methylome in two human colon cancer derived cell lines, two human normal bone marrow CD34+ controls and in five human Acutre Myeloid Leukeima patient samples. These data can be used to determine the CpG cytosine methylation pattern ...
ORGANISM(S): Homo sapiens 
2012-06-01 | E-GEOD-37454 | biostudies-arrayexpress
GenomicsEGAS00001000262-sc-20170314 - samples
Whole Genome Sequencing Illumina HiSeq data from 111 men with prostate cancer. Samples were taken from primary tissue obtained at prostatectomy (target sequencing depth 50X) with matched blood control (target sequencing depth 30X). This data is from batches 4 to 6.
EGAD00001003225 | EGA
GenomicsThe Natural History of Human Prostate Cancer - samples
Affymetrix SNP6.0 genotype data for prostate cancer patients
EGAD00010000498 | EGA
GenomicsEGAS00001000262-sc-20160408 - samples
To characterize the subclonal genomic architecture of non-androgen-deprived metastatic prostate cancer, we performed whole-genome sequencing (WGS) of pelvic lymph node metastases and matching noncancerous blood from 10 patients to an average sequencing depth of 55x. The patients are part of PELICAN ...
EGAD00001002002 | EGA
GenomicsEGAS00001000262-sc-20131030 - samples
Whole genome DNA sequencing was used to decrypt the phylogeny of multiple samples from distinct areas of cancer and morphologically normal tissue taken from the prostates of 3 men. For each of three different prostates, multiple tumour samples (4, 5, and 3 depending on the case) and one normal tissu...
EGAD00001000689 | EGA
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