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TranscriptomicsIn vivo LPS responses in murine splenic CD8 and CD11b DC subsets
Background: Dendritic cells (DCs) are critical for regulating CD4 and CD8 T cell immunity, controlling Th1, Th2, and Th17 bias, generating inducible Tregs, and inducing tolerance. Multiple DC subsets have been identified in the mouse that are thought to have evolved to control these different immune...
ORGANISM(S): Mus musculus 
2014-07-01 | E-GEOD-42573 | biostudies-arrayexpress
Proteomics,MultiomicsCyclin C-CDK3/8/19 kinases play a tumor-suppressive role in vivo
Cyclin C was cloned as a growth-promoting G1 cyclin1,2, and several studies postulated a role for cyclin C in driving cell proliferation3-8 . Moreover, cyclin C, together with its kinase partner, the cyclin-dependent kinase CDK8, is believed to represent an essential component of basal transcrip...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080728 | MassIVE
UnknownCRAFT (Cerclage after full dilatation caesarean section): protocol of a mixed methods study investigating the role of previous in-labour caesarean section in preterm birth risk.
Not available
S-EPMC7667480 | biostudies-literature
TranscriptomicsTranscription profiling of human macrophages and dendritic cells exposed to phylogenetically distinct parasites
Monocyte-derived dendritic cells (DC) and macrophages (MΦ) generated in vitro from the same individual blood donors were exposed to five different pathogens, and gene expression profiles were assessed by microarray analysis. Responses to Mycobacterium tuberculosis and to phylogenetically distinct ...
ORGANISM(S): Homo sapiens 
2007-12-13 | E-GEOD-360 | biostudies-arrayexpress
TranscriptomicsSex-dependent gene regulatory networks of the heart rhythm
Expression level, control and intercoordination of 66 selected heart rhythm determinant (HRD) genes were compared in atria and ventricles of 4 male and 4 female adult mice. We found that genes encoding various adrenergic receptors, ankyrins, ion channels and transporters, connexins and other compone...
ORGANISM(S): Mus musculus 
2009-08-12 | E-GEOD-17324 | biostudies-arrayexpress
UnknownMolecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.
Not available
S-EPMC4356709 | biostudies-literature
UnknownEpacadostat Plus Pembrolizumab in Patients With Advanced Solid Tumors: Phase I Results From a Multicenter, Open-Label Phase I/II Trial (ECHO-202/KEYNOTE-037).
Not available
S-EPMC6225502 | biostudies-literature
UnknownVismodegib Exerts Targeted Efficacy Against Recurrent Sonic Hedgehog-Subgroup Medulloblastoma: Results From Phase II Pediatric Brain Tumor Consortium Studies PBTC-025B and PBTC-032.
Not available
S-EPMC4534527 | biostudies-literature
OtherA Method for Large-scale Identification of Protein Arginine Methylation
PASSEL ID: PASS00081. Original data file: B100910_042.mzXML. Data published as part of Mol Cell Proteomics. 2012 11:1489-99 . From the Abstract: {{i}} ... Here we show that most tryptic peptides containing methylated arginine(s) are highly basic and hydrophilic. Consequently, they could be consider...
ORGANISM(S): Human 
GPM11210008866 | GPMDB
UnknownInduction chemotherapy and conformal radiation therapy for very young children with nonmetastatic medulloblastoma: Children's Oncology Group study P9934.
Not available
S-EPMC3434977 | biostudies-literature
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