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In plants, MAPKs are implicated in signalling cascades regulating immediate as well as systemic responses to pathogens. Arabidopsis MAP kinase 4 (MPK4) negatively regulates systemic acquired resistance (SAR) accompanied by the expression of pathogenesis-related (PR) genes. MPK4 interacts with and ph...
ORGANISM(S): Arabidopsis thaliana 
The T-cell receptor (TCR) initiates T-lymphocyte activation, but the mechanism of TCR activation remains uncertain. Here, we present cryogenic electron microscopy structures for the unliganded and human leukocyte antigen (HLA)-bound human TCR–CD3 complex in nanodiscs that provide a native-like lipid...
ORGANISM(S): Homo sapiens (Human) 
2025-12-17 | PXD070648 | Pride
transriptional profiling of Bacillus subtilis treated with Plectasin
ORGANISM(S): Bacillus subtilis strain 168 
Data from ProteomeXchange, PXD ID: PXD000746. Experiment: label-free, file: 2012-10-05 - ETP - Fuchs - Control - 3-2.mgf. Published as part of J Proteome Res. 2014 May 21 . From the Abstract: {{i}} Fuchs- endothelial corneal dystrophy (FECD) is a major corneal disorder affecting the innermost part ...
ORGANISM(S): Homo_sapiens_viruses, Human 
Duchenne muscular dystrophy (DMD) is a classical monogenic disorder, a model disease for genomic studies and a priority candidate for regenerative medicine and gene therapy. Although the genetic cause of DMD is well known, the molecular pathogenesis of disease and the response to therapy are incompl...
ORGANISM(S): Mus musculus 
Matched control samples using HumanOmni1-Quad
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