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TranscriptomicsMicroarray of A375, MDAMB468, SUM52PE, SKBR3, T47D, HCC827 and MKN45 cancer cell lines treated with rapamycin compared to DMSO-treated control
Comparison of gene expression in cancer cell lines treated with rapamycin for 24h compared to DMSO
ORGANISM(S): Homo sapiens 
2020-07-31 | E-MTAB-8727 | biostudies-arrayexpress
ProteomicsOrganelle resolved proteomics reveals new chordoma cell surface markers required for proliferation and association with outcome
Here, we used a proteomics approach to identify novel chordoma-specific cell-surface protein markers. Four established chordoma cell lines (U-CH17P, U-CH17M, U-CH17S and U-CH11R) were analyzed by quantitative proteomics using a comprehensive organellar fractionation approach based on differential ul...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2022-03-31 | MSV000089171 | MassIVE
TranscriptomicsRNA-seq of human breast cancer cell line MCF-7 treated for 24h with rapamycin or DMSO
Investigation of differential pre-mRNA splicing in breast cancer cell line MCF-7 treated with rapamycin compared to vehicle DMSO that are overexpressing TRIB3
ORGANISM(S): Homo sapiens 
2020-07-31 | E-MTAB-8726 | biostudies-arrayexpress
UnknownDelineation and agreement of FET PET biological volumes in glioblastoma: results of the nuclear medicine credentialing program from the prospective, multi-centre trial evaluating FET PET In Glioblastoma (FIG) study-TROG 18.06.
Not available
S-EPMC10611835 | biostudies-literature
TranscriptomicsTranscriptional profiling of Ewing's sarcoma derived exosomes
Exosomes are small RNA and protein containing vesicles that can mediate hetero- and homotypic intercellular communication between normal and malignant cells. Especially, tumor-derived exosomes are believed to mediate reprogramming of the tumor-associated stroma to favor tumor growth and metastasis. ...
ORGANISM(S): Homo sapiens 
2013-05-01 | E-GEOD-42282 | biostudies-arrayexpress
TranscriptomicsATAC-seq with and without siRNA ORF1 in post-mitotic human dopaminergic neurons (LUHMES cell line, differentiated)
LINE-1 are the only active and autonomous transposable elements in the human genome and encode two proteins, the nucleic acid chaperone ORF1p and ORF2p, which has reverse transcriptase and endonuclease activities. ORF1p is present at steady-state in human and mouse neurons in the adult brain, but a ...
ORGANISM(S): Homo sapiens 
2026-04-01 | E-MTAB-15871 | biostudies-arrayexpress
TranscriptomicsMondoA is highly expressed in acute lymphoblastic leukemia and modulates metabolism, differentiation and survival
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. To identify novel candidates for targeted treatment of childhood ALL, we performed a comprehensive transcriptome analysis yielding a set of genes specifically overexpressed in ALL. Among them we identified MondoA - a transcripti...
ORGANISM(S): Homo sapiens 
2012-07-31 | E-GEOD-33967 | biostudies-arrayexpress
TranscriptomicsTargeting IRAK1 as a therapeutic approach for Myelodysplastic Syndrome
Myelodysplastic Syndromes (MDS) result from expansion of defective hematopoietic stem/progenitor clones. There is an urgent need to develop targeted therapies capable of eliminating the defective MDS clones. We identified that IRAK1, an immune modulating kinase, is overexpressed and hyperactivated i...
ORGANISM(S): Homo sapiens 
2013-04-25 | E-GEOD-46346 | biostudies-arrayexpress
UnknownAntibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab.
Not available
S-EPMC8927425 | biostudies-literature
TranscriptomicsMitochondrial carrier SLC25A34 links clock, diet, and temperature control of adipocyte lipid cycling
Transcriptome from immortalized murine brown adipocytes BMC. Cells were transfected with siRNA construct #1 or construct #2 (pool) or non-targeting control on day 3 of differentiation and harvested on day 7 of differentiation.
ORGANISM(S): Mus musculus 
2026-09-23 | E-MTAB-17577 | biostudies-arrayexpress
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