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GenomicsGenome-wide identification of Ikaros binding sites in pre-B cells
Ikaros DNA binding proteins are important regulators of haematopoiesis and genetic deletion of Ikaros results in severe developmental disturbances, including delayed thymocyte differentiation and an early and complete block in B cell development. Although Ikaros ChIP-seq data are available for mouse...
ORGANISM(S): Mus musculus 
2013-01-15 | E-GEOD-38169 | biostudies-arrayexpress
TranscriptomicsGene expression in mouse primary pre-B cells transduced with Ikaros
Ikaros family DNA binding proteins are critical regulators of B cell development. To identify Ikaros-regulated genes in primary pre-B cells we performed gene expression microarrays. We used retroviral gene transfer to express Ikaros proteins. Total RNA from 3 biological replicates of primary pre-B c...
ORGANISM(S): Mus musculus 
2013-01-15 | E-GEOD-42551 | biostudies-arrayexpress
TranscriptomicsGene expression in mouse pre-B cells transduced with Ikaros.
Ikaros family DNA binding proteins are critical regulators of B cell development. To identify Ikaros-regulated genes in pre-B cells we performed gene expression studies at enhanced temporal resolution. We used retroviral gene transfer to express Ikaros proteins in the pre-B cell line B3. Total RNA f...
ORGANISM(S): Mus musculus 
2013-01-15 | E-GEOD-38110 | biostudies-arrayexpress
TranscriptomicsEpigenetic changes in B lymphocytes associated with house dust mite allergic asthma.
The increase in atopic diseases has occurred in such a short period of time that it becomes difficult to be attributed only to genetic factors, which usually need more prolonged time periods to manifest. In this setting during the last decade, the science of epigenetics has increasingly developed of...
ORGANISM(S): Homo sapiens 
2011-12-01 | E-GEOD-26080 | biostudies-arrayexpress
TranscriptomicsMassively Parallel Sequencing Identifies the MicroRNA Transcriptome of Normal and Malignant Human B cells
Profiling of miRNA transcriptome in Human mature B cells from similar populations Profiling of miRNA transcriptome in Human Normal and Malignant B cells, 8 normal samples corresponding to Naïve, Germinal Center, Plasma and Memory B cells and 23 samples derived from B cell malignancy
ORGANISM(S): Homo sapiens 
2010-08-25 | E-GEOD-15229 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling in primary Diffuse Large B cell Lymphoma (DLBCL) and normal Germinal Center B Cells
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study we carried out genome-wide DNA methylatio...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54200 | biostudies-arrayexpress
TranscriptomicsDeep Sequencing of the Small RNA Transcriptome of Normal and Malignant Human B cells Identifies Hundreds of Novel MicroRNAs: microarray analysis
A role for microRNAs has been recognized in nearly every biological system examined thus far. A complete delineation of their role must be preceded by the identification of all microRNAs present in any system. We elucidated the complete small RNA transcriptome of normal and malignant B cells through...
ORGANISM(S): Homo sapiens 
2010-08-26 | E-GEOD-22895 | biostudies-arrayexpress
GenomicsIkaros target genes in the mouse pre-B cell line B3
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-01-15 | E-GEOD-38200 | biostudies-arrayexpress
ProteomicsComparative proteomics of salt stressed own rooted and 110R grafted Thompson Seedless grapevines
Salt stress is a rising threat to agriculture system. The accumulation of salts near the plant roots hampers the normal uptake of water causing osmotic stress and ionic toxicity to the plant. Thompson Seedless is a popular table grape variety of Vitis vinifera L., which is sensitive to salt stress w...
ORGANISM(S): Vitis vinifera (Grape) 
2020-01-27 | PXD015515 | Pride
Lc-msms Thompson seedless Vitis : label-free Synapt-g1 Hdms Salt stress Shotgun Grapevine Leaf Progenesis-qip 
UnknownThe electroretinogram b-wave amplitude: a differential physiological measure for Attention Deficit Hyperactivity Disorder and Autism Spectrum Disorder.
Not available
S-EPMC9077889 | biostudies-literature
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