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UnknownMarked expansion of exocrine and endocrine pancreas with incretin therapy in humans with increased exocrine pancreas dysplasia and the potential for glucagon-producing neuroendocrine tumors.
Not available
S-EPMC3712065 | biostudies-literature
UnknownLoss of Insulin-Positive Cell Clusters Precedes the Decrease in Islet Frequency and β-Cell Area in Type 1 Diabetes.
Not available
S-EPMC12585168 | biostudies-literature
TranscriptomicsThe effect of dietary CLA on mammary tumorigenesis
Conjugated linoleic acid (CLA), a class of fatty acids found in beef and dairy products, has been shown to inhibit tumorigenesis in a variety of cancer model systems. Based on previously well-documented anti-tumor activity of CLA in rodent models of breast cancer, a pilot study was initiated to exam...
ORGANISM(S): Mus musculus 
2008-11-18 | E-GEOD-13553 | biostudies-arrayexpress
TranscriptomicsTGF-beta-mediated microRNA expression in breast cancer cells
We utilized 3D-organotypic cultures whose physical properties were altered by inclusiong of type I collagen to create biomechanically rigid microenvironments that approximated those typically observed in primary mammary tumors. Compliant 3D-organotypic cultures were also generated to recapitulate t...
ORGANISM(S): Mus musculus 
2012-10-31 | E-GEOD-41274 | biostudies-arrayexpress
TranscriptomicsCommon Gene Transcriptional Patterns Following Immobilization, Spinal Cord Injury, and Unloading in Human Skeletal Muscle
Following spinal cord injury, skeletal muscle loss is rapid. This severe atrophy is attributed to declines in protein synthesis and increases in protein breakdown. However, the signaling mechanisms controlling these changes are not well understood. Nine male patients and one female patient with spin...
ORGANISM(S): Homo sapiens 
2010-10-23 | E-GEOD-21497 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of individual bovine nuclear transfer blastocysts
Individual zona free in vitro grown bovine day 7 blastocysts were compared to stage and quality matched nuclear transfer derived blastocysts (fibroblast donor cells).
ORGANISM(S): Bos taurus 
2006-02-14 | E-MEXP-556 | biostudies-arrayexpress
UnknownStratification of Pancreatic Ductal Adenocarcinoma: Combinatorial Genetic, Stromal, and Immunologic Markers.
Not available
S-EPMC5951386 | biostudies-literature
TranscriptomicsAn Integrated Model of the Transcriptome Landscape of HER2-Positive Breast Cancer
The goal of our study is to build an integrated transcriptome landscape model for HER2 positive breast tumors and identify the crucial signaling pathways associated with HER2 tumors. Genomic features include, 685 genes that were differentially expressed only in HER2-positive tumors, 102 genes that w...
ORGANISM(S): Homo sapiens 
2013-12-06 | E-GEOD-45419 | biostudies-arrayexpress
TranscriptomicsDNA methylation profiling in primary Diffuse Large B cell Lymphoma (DLBCL) and normal Germinal Center B Cells
Diffuse Large B-Cell Lymphoma (DLBCL) is the most common aggressive form of non-Hodgkin lymphoma with variable biology and clinical behavior. The current classification does not fully explain the biological and clinical heterogeneity of DLBCLs. In this study we carried out genome-wide DNA methylatio...
ORGANISM(S): Homo sapiens 
2014-01-18 | E-GEOD-54200 | biostudies-arrayexpress
UnknownAssociation of the IL2RA/CD25 gene with juvenile idiopathic arthritis.
Not available
S-EPMC2963023 | biostudies-literature
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