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TranscriptomicsExpression data from Parkison's iPSCs with four copies of SNCA, and equivalent cell lines from an unaffected first degree relative
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-30792 | biostudies-arrayexpress
TranscriptomicsSNP data from genomic DNA from a subject, fibroblasts, iPSCs and neurons with four copies of SNCA, and genomic DNA from an unaffected first degree relative and equivalent cell lines
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-28366 | biostudies-arrayexpress
TranscriptomicsExpression data from fibroblasts, iPSCs and neurons with four copies of SNCA, and equivalent cell lines from an unaffected first degree relative
A major barrier to research on Parkinson’s disease (PD) is inaccessibility of diseased tissue for study. One solution is to derive induced pluripotent stem cells (iPSCs) from patients with PD and differentiate them into neurons affected by disease. We created an iPSC model of PD caused by triplicati...
ORGANISM(S): Homo sapiens 
2011-09-14 | E-GEOD-28365 | biostudies-arrayexpress
MetabolomicsAlignment of multiple metabolomics LC-MS datasets from disparate diseases to reveal fever-associated metabolites

Acute febrile illnesses are still a major cause of mortality and morbidity globally, particularly in low to middle income countries. The aim of this study was to determine any possible metabolic commonalities of patients infected with disparate pathogens that cause fever. Three liquid chromatogra...

2023-07-17 | MTBLS4895 | MetaboLights
ProteomicsAutomating Multidimensional Liquid Chromatography, Ion Mobility Spectrometry and Mass Spectrometry Data Analyses Using Skyline
Recent advances in ion mobility spectrometry (IMS) have illustrated its power in the structural characteristics of a molecule, especially when coupled with other separations dimensions such as liquid chromatography (LC) and mass spectrometry (MS). However, these three separation techniques together ...
ORGANISM(S): Bos Taurus Saccharomyces Cerevisiae 
PXD010650 | panorama
ProteomicsProbing the Sensitivity of the Lumos Mass Spectrometer by analyzing varying amounts of whole cell extracts
PROJECT DESCRIPTION The Orbitrap Fusion Lumos mass spectrometer has recently been shown to have better fragmentation and detection than its predecessors. Previous studies using a HeLa digest analyzed on the Lumos mass spectrometer have reported the number of peptides and proteins identified by rever...
ORGANISM(S): Saccharomyces Cerevisiae (ncbitaxon:4932) 
2018-04-19 | MSV000082296 | MassIVE
UnknownImpact of Complete Revascularization in the ISCHEMIA Trial.
Not available
S-EPMC10529674 | biostudies-literature
UnknownCanvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space.
Not available
S-EPMC6311695 | biostudies-literature
UnknownIntegrative analysis of 111 reference human epigenomes.
Not available
S-EPMC4530010 | biostudies-literature
UnknownRecurrent gain-of-function mutation in PRKG1 causes thoracic aortic aneurysms and acute aortic dissections.
Not available
S-EPMC3738837 | biostudies-literature
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