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ProteomicsProteomics data reveals Wnt signaling involvement in the hippocampal-dependent behavioral impairment in THRSP-overexpressing ADHD mouse model
Despite the predominance and high heritability of Attention-Deficit/Hyperactivity Disorder (ADHD), its etiology remains elusive. Preclinical and clinical evidence partly points to impaired limbic system function, particularly that of the hippocampus (HPC). Children diagnosed with ADHD often struggle...
ORGANISM(S): Mus musculus (Mouse) 
2023-01-18 | PXD038525 | Pride
Thrsp Mus musculus Lc-ms/ms 
UnknownThe Thrsp null mouse (Thrsp(tm1cnm)) and diet-induced obesity.
Not available
S-EPMC2671690 | biostudies-literature
ProteomicsStriatal proteomics offers clues on the inattention in early adult THRSP-overexpressing mice: Involvement of Snap25 gene
Attention-deficit/hyperactivity disorder, or ADHD, is a neurodevelopmental disorder characterized by inattention, hyperactivity, and impulsivity. Despite its high prevalence, the underlying molecular mechanisms of ADHD remain poorly understood. Recent studies have proposed that changes in the expres...
ORGANISM(S): Mus musculus (Mouse) 
2025-09-22 | PXD051619 | Pride
Animal model Thrsp-oe mice Snare complex Snap25 Thyroid hormone-response protein Adult adhd 
GenomicsMIF-mediated crosstalk between Thrsp+ hepatocytes and Cd74+ lipid-associated macrophages in hepatic periportal zone drives MASH
MIF-mediated crosstalk between Thrsp+ hepatocytes and Cd74+ lipid-associated macrophages in hepatic periportal zone drives MASH
PRJNA1243342 | ENA
OtherMIF-mediated crosstalk between Thrsp+ hepatocytes and Cd74+ lipid-associated macrophages in hepatic periportal zone drives MASH
Background & Aims: Spatial location of steatosis is closely related to the progression of metabolic dysfunction-associated steatohepatitis (MASH), and reports suggest lipid-associated macrophages (LAMs) facilitate this progression. However, the underling mechanisms remain elusive. Approach & Results...
ORGANISM(S): Mus musculus 
2025-12-05 | GSE293203 | GEO
UnknownInsulin-inducible THRSP maintains mitochondrial function and regulates sphingolipid metabolism in human adipocytes.
Not available
S-EPMC9204892 | biostudies-literature
UnknownDownregulation of THRSP Promotes Hepatocellular Carcinoma Progression by Triggering ZEB1 Transcription in an ERK-dependent Manner.
Not available
S-EPMC8176411 | biostudies-literature
UnknownTHRSP identified as a potential hepatocellular carcinoma marker by integrated bioinformatics analysis and experimental validation.
Not available
S-EPMC8908915 | biostudies-literature
UnknownIncreased expression of thyroid hormone responsive protein (THRSP) is the result but not the cause of higher intramuscular fat content in cattle.
Not available
S-EPMC5441172 | biostudies-literature
UnknownHippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model.
Not available
S-EPMC9842619 | biostudies-literature
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