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ORGANISM(S): Homo sapiens 
The transport of molecules via exosomes is one of the factors involved in cancer development, and transferred molecules can serve as specific tumor biomarkers. The aim of the study was the LC MS/MS proteomic analysis of exosomes released by FTC and 8305C thyroid cancer cell lines, and reference Nthy...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2023-10-19 | MSV000093152 | MassIVE
We show that numerous miRNAs are transcriptionally up-regulated in papillary thyroid carcinoma (PTC) tumors compared with unaffected thyroid tissue. Among the predicted target genes of the three most upregulated miRNAs (miRs 221, 222 and 146b), only less than 15% showed significant downexpression i...
ORGANISM(S): Homo sapiens 
This project aims to explore the protein interaction network of thyroid cancer cell lines through a robotics platform combined with proteomic techniques. The primary method involves using CF-DIA-MS (Co-fractionation Data-Independent Acquisition Mass Spectrometry) to acquire data from three different...
ORGANISM(S): Homo sapiens (Human) 
2025-12-20 | PXD059608 | Pride
ChIP-seq experiment was performed using an antibody against E2F7 in CAL62 anaplastic thyroid cancer cell line, in order to define the genomic regions bound by this transcription factor and exploit its genomic function in this cancer setting.
ORGANISM(S): Homo sapiens 
In this study, we profiled the change of gene expression by p53 knock-down on anaplastic thyroid carcinoma (ATC) cell line, KAT-18 cells using Applied Biosystem's Microarrays. When compared with the untreated control KAT-18 cells, 2,926 genes were found to have altered expression levels of 2-fold or...
ORGANISM(S): Homo sapiens 
Human thyroid cancer cell line BCPAP was engineered for doxycyclin-mediated inducible expressoin of Prox1 and next generation sequcing was performed to study the transcriptional regulation by Prox1 BCPAP cells were infected with rTTA2 lentivirus. The resulting cell populations were then stably trans...
ORGANISM(S): Homo sapiens 
Thyroid ultrasound and ultrasound-guided fine-needle aspiration (USG/FNA) biopsy are currently used for diagnosing papillary thyroid carcinoma (PTC), but their detection limit could be improved by combining other biomarkers. To discover novel PTC biomarkers, we herein applied a GeLC-MS/MS strategy t...
ORGANISM(S): Homo sapiens (Human) 
2018-03-21 | PXD007532 | Pride
Recurrent non-medullary thyroid carcinoma (NMTC) is a rare disease. We initially characterized 27 recurrent NMTC: 13 papillary thyroid cancers (PTC), 10 oncocytic follicular carcinomas (FTC-OV), and 4 non-oncocytic follicular carcinomas (FTC). A validation cohort composed of benign and malignant (bo...
ORGANISM(S): Homo sapiens 
Transcriptional analysis of 49 primary medullary thyroid carcinoma tumors. Comparisons MTCM918T vs MTC634 and MTCM918T vs MTCWT. 49 (52 hybridized tumors with 3 replicates) primary Medullary Thyroid Carcinoma (MTC) cases were hybridized onto a cDNA microarray in order to identify the unique markers ...
ORGANISM(S): Homo sapiens 
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