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Premature ovarian insufficiency (POI) impairs fertility and health in reproductive-age women, with autoimmune factors contributing to 4-30% of cases[1]. To investigate immune dysregulation in POI, we developed two mouse models using pZP3 induction: regular immune (RE-POI) and enhanced immune (EN-POI...
ORGANISM(S): Mus Musculus 
2026-04-20 | PXD077415 |
To investigate the proteomic features in lean subjects with NAFLD, and to identify possible plasma proteins that provide potential application for diagnosing of NAFLD in lean individuals. Participants with or without NAFLD were divided into an overweight NAFLD group, an overweight control group, a l...
ORGANISM(S): Homo Sapiens 
2022-07-21 | PXD035514 |
The protein corona formed on the surface of nanomaterials is critical to understanding their biological behavior, as it is regulated by both the physicochemical properties of the nanomaterials and the physiological environment. The interplay between material synthesis characteristics, protein corona...
ORGANISM(S): Homo Sapiens 
2024-10-14 | PXD056769 |
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor prognosis. Only limited data are available concerning potential noninvasive biomarkers for disease monitoring. Here, we investigated the proteomic profile of plasma in 362 UTUC patients and 239 healthy control samples....
ORGANISM(S): Homo Sapiens 
2023-07-12 | PXD043774 |
Comprehensive proteogenomic analysis of Microphthalmia Transcription Factor (MiT) family translocation renal cell carcinoma (tRCC) tumor and normal adjacent tissues was performed to elucidate the molecular landscape of these tumors.
ORGANISM(S): Homo Sapiens 
2022-07-20 | PXD035377 |
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