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We develop a method with high sensitivity and reproducibility to comprehensively illustrated the glycosylation of plasma CEA based on trifunctional probe and multi-enzymatic approach. Site-specific glycoforms of plasma CEA differed in patients with different cancers and the progression of CRC.
ORGANISM(S): Homo Sapiens 
2023-10-31 | PXD046518 |
In this study, we analyzed transcriptome gene expression microarray, epigenomic miRNA microarray and methylome sequencing data simultaneously in PBMs from 5 high hip BMD subjects and 5 low hip BMD subjects. Through integrating the transcriptomic and epigenomic data, firstly we identified BMD-related...
ORGANISM(S): Homo sapiens 
Thirteen paired pre- and post-nCRT sera from rectal cancer patients were analyzed by isobaric tags for relative and absolute quantitation (iTRAQ) method. Twenty-five proteins were selected for validation by parallel reaction monitoring (PRM) in ninety-one patients.
ORGANISM(S): Homo Sapiens 
2022-03-08 | PXD032117 |
RNA polymerase II (Pol II) subunits are thought to be involved in various transcription-associated processes, but it is unclear whether they play different regulatory roles in modulating gene expression. Here, we performed nascent and mature transcript sequencing after the acute degradation of 12 ma...
ORGANISM(S): Mus <genus> 
2022-08-09 | PXD035866 |
Colorectal cancer is the 3rd commonly diagnosed cancer (10.2%) and 2nd cause of cancer death (9.2%) in all cancers.There will be estimated 1.8 million new colorectal cancer cases and 0.9 million colorectal cancer deaths in 20181. As the 5th incidence rates and mortality rates cancer in china, colore...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032291 |
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