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The outbreak of coronavirus disease 2019 (COVID-19) is a global health emergency. Various omics results have been reported for COVID-19, but the molecular hallmarks of COVID-19, especially in those patients without comorbidities, have not been fully investigated. Here we collect blood samples from 2...
2021-10-06 | MTBLS2542 | MetaboLights
In this study, we provided a comprehensive lifespan characterization of urine metabolomics in a cohort of 348 healthy children and 315 adults aged 1 to 70 years using liquid chromatography coupled with high resolution mass spectrometry.
ORGANISM(S): Homo Sapiens 
2022-06-06 | PXD034390 |
We present the first comprehensive proteomic and phosphoproteomic atlas of nine major organs of the Chinese hamster (Cricetulus griseus). A total of 14,219 proteins, 11,828 phosphorylated proteins, and 47,122 phosphorylation sites were identified, revealing distinct inter-organ molecular features.
ORGANISM(S): Cricetulus Griseus 
2025-10-04 | PXD069241 |
we compared the interacting proteins between Hsc70-WT and Hsc70-3KA using mass spectrometry to discover additional mediators of this process
ORGANISM(S): Homo Sapiens 
2024-04-05 | PXD051241 |
Colorectal cancer is the 3rd commonly diagnosed cancer (10.2%) and 2nd cause of cancer death (9.2%) in all cancers.There will be estimated 1.8 million new colorectal cancer cases and 0.9 million colorectal cancer deaths in 20181. As the 5th incidence rates and mortality rates cancer in china, colore...
ORGANISM(S): Homo Sapiens 
2022-03-15 | PXD032291 |
Lithocholic acid (LCA), accumulated in mammals during calorie restriction (CR), can activate AMP-activated protein kinase (AMPK) and slow down ageing1. However, how LCA is signalled to activate AMPK and elicit the biological effects is unclear. Here, we show that LCA can enhance the activity of sirt...
ORGANISM(S): Homo Sapiens Mus Musculus 
2024-09-16 | PXD056134 |
Metformin is the most prescribed anti-diabetic medicine, and has also been shown to have other various benefits, such as anti-aging and anti-cancer effects. For clinical doses of metformin, it is known that AMPK plays a major role; however, the direct molecular target of metformin remains unclear. H...
ORGANISM(S): Homo Sapiens Mus Musculus 
2021-12-01 | PXD030090 |
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