Sort   by:  
 Page size 
TranscriptomicsGenome-wide measurement of RNA folding energies
RNA structural transitions are important in the function and regulation of RNAs. Here, we reveal a layer of transcriptome organization in the form of RNA folding energies. By probing yeast RNA structures at different temperatures, we obtained relative melting temperatures (Tm) for RNA structures in ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-09-09 | E-GEOD-39680 | biostudies-arrayexpress
TranscriptomicsDifferential Gene Expression Profiles in CD34+ Myelodysplastic Syndrome Marrow cells to Disease Subtype and Progression
Microarray analysis with 40,000 cDNA gene chip arrays determined differential gene expression profiles (GEPs) in CD34+ marrow cells from myelodysplastic syndrome (MDS) patients compared to normal individuals. Using focused bioinformatics analyses, we found 1175 genes significantly differentially ex...
ORGANISM(S): Homo sapiens 
2009-10-31 | E-GEOD-18366 | biostudies-arrayexpress
TranscriptomicsUltra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumors and matched controls
We prepared small RNA libraries from 29 tumor/normal pairs of human cervical tissue samples. Analysis of the resulting sequences (42 million in total) defined 64 new human microRNA (miRNA) genes. Both arms of the hairpin precursor were observed in twenty-three of the newly identified miRNA candidate...
ORGANISM(S): Homo sapiens 
2010-04-28 | E-GEOD-20592 | biostudies-arrayexpress
UnknownActive idiotypic vaccination versus control immunotherapy for follicular lymphoma.
Not available
S-EPMC4039868 | biostudies-literature
UnknownA network model of a cooperative genetic landscape in brain tumors.
Not available
S-EPMC4447713 | biostudies-literature
MetabolomicsPlasma Lipidomics Identifies Anticedent Memory Impairment in Older Adults
Alzheimer's disease causes a progressive dementia that currently affects over 35 million individuals worldwide and is expected to affect 115 million by 2050 (ref. 1). There are no cures or disease-modifying therapies, and this may be due to our inability to detect the disease before it has progresse...
2014-03-09 | MTBLS72 | MetaboLights
TranscriptomicsTranscription profiling of human lymphoblastoid cells from patients with limited or acute radiation toxicity, skin cancer patients and normal controls, exposed to UV or IR light
Peripheral blood lymphocytes from a total of 57 patients were immortalized with Epstein-Barr virus. Fourteen radiation-therapy patients suffered unusual levels of radiation toxicity (RadS). Thirteen radiation-therapy patients with limited toxicity (RadC) were enrolled as controls. Fifteen patient...
ORGANISM(S): Homo sapiens 
2007-08-05 | E-GEOD-1725 | biostudies-arrayexpress
ProteomicsPhosphatases modified by LH signaling in ovarian follicles: testing their role in regulating the NPR2 guanylyl cyclase
In response to luteinizing hormone (LH), multiple proteins in rat and mouse granulosa cells are rapidly dephosphorylated, but the responsible phosphatases remain to be identified. Because the phosphorylation state of phosphatases can regulate their interaction with substrates, we searched for phosph...
ORGANISM(S): Rattus norvegicus (Rat) 
2023-11-20 | PXD033878 | Pride
Ovarian follicle Chondrocytes Luteinizing hormone Npr2 Fibroblast growth factor Phosphorylation Cyclic gmp 
TranscriptomicsA shared transcriptional program in early breast neoplasias despite genetic and clinical distinctions
The earliest recognizable stages of breast neoplasia are lesions that represent a heterogeneous collection of epithelial proliferations currently classified based on morphology. Their role in the development of breast cancer is not well understood but insight into the critical events at this early s...
ORGANISM(S): Homo sapiens 
2014-05-04 | E-GEOD-47462 | biostudies-arrayexpress
UnknownGenomic responses in mouse models poorly mimic human inflammatory diseases.
Not available
S-EPMC3587220 | biostudies-literature
Sort   by:  
 Page size