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TranscriptomicsIntegrated ordination of miRNA and mRNA expression profiles [mRNA]
Several studies have shown that negative and positive miRNA-mRNA correlations are symmetrically distributed. While negative correlations are consistent with a faster degradation of miRNA targets, the presence of positive correlations suggests bidirectional interactions between the two classes of mol...
ORGANISM(S): Homo sapiens 
2015-10-08 | E-GEOD-62029 | biostudies-arrayexpress
TranscriptomicsLiver Regeneration Gene Signature in Hepatitis B virus (HBV)-Associated Acute Liver Failure Identified by Gene Expression Profiling
The liver has inherent regenerative capacity via mitotic division of mature hepatocytes. However, if the hepatic loss is massive or mature hepatocyte proliferation is impaired by chronic liver injury, HSPC are activated to support liver regeneration. Access to liver tissue from 4 patients who underw...
ORGANISM(S): Homo sapiens 
2012-12-01 | E-GEOD-38941 | biostudies-arrayexpress
TranscriptomicsB-Cell Gene Signature with Massive Intrahepatic Production of Antibodies to Hepatitis B Core Antigen in HBV-Associated Acute Liver Failure
Hepatitis B virus (HBV)-associated acute liver failure (ALF) is a dramatic clinical syndrome due to a sudden loss of hepatic cells leading to multiorgan failure. The mechanisms whereby HBV induces ALF are unknown. We used gene expression profiling to establish a molecular definition of hepatitis B v...
ORGANISM(S): Homo sapiens 
2010-04-26 | E-GEOD-14668 | biostudies-arrayexpress
TranscriptomicsIdentification of microRNAs specifically expressed in HCV-associated hepatocellular carcinoma
Background: Several studies have investigated the association of miRNAs with hepatocellular carcinoma (HCC) but the data are not univocal. Methods: We performed a microarray study of miRNAs in hepatitis C virus (HCV)-associated HCC and other liver diseases and healthy conditions. Results and Concl...
ORGANISM(S): Homo sapiens 
2013-02-20 | E-GEOD-40744 | biostudies-arrayexpress
TranscriptomicsViral Expression and Molecular Profiling in Liver Tissue versus Microdissected Hepatocytes in Hepatitis B Virus - Associated Hepatocellular Carcinoma
The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by mapping the entire liver of patients with HCC. We compared the gene signature of whole liver tissue (WLT)...
ORGANISM(S): Homo sapiens 
2014-12-22 | E-GEOD-55092 | biostudies-arrayexpress
UnknownWhole-Body Hypothermia for Neonatal Encephalopathy in Preterm Infants 33 to 35 Weeks' Gestation: A Randomized Clinical Trial.
Not available
S-EPMC11851295 | biostudies-literature
UnknownExtended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial.
Not available
S-EPMC12038711 | biostudies-literature
UnknownSocial Determinants of Health and Redirection of Care for Infants Born Extremely Preterm.
Not available
S-EPMC10928542 | biostudies-literature
UnknownIncidence of and Neurodevelopmental Outcomes After Late-Onset Meningitis Among Children Born Extremely Preterm.
Not available
S-EPMC9856224 | biostudies-literature
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