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TranscriptomicsLarge intergenic non-coding RNAs as novel modulators of reprogramming: human embryonic stem cells, fibroblasts, and fibroblast-derived induced pluripotent stem cells (LincRNA expression)
Expression profiling of non coding RNAs using tilling arrays from ES, Fibroblasts and Fibroblasts derived iPSC LincRNA profiles of human embryonic stem cells, fibroblasts, and fibroblast-derived induced pluripotent stem cells Total RNA was extracted from human ESCs, fibroblast, and fibroblast-derive...
ORGANISM(S): Homo sapiens 
2010-11-10 | E-GEOD-24181 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse NFIA deficient mice brain
Background. Nuclear factor I-A (NFI-A), a phylogenetically conserved transcription/replication protein, plays a crucial role in mouse brain development. Previous studies showed that disruption of the Nfia gene in mice leads to perinatal lethality, corpus callosum agenesis, and hydrocephalus. Result...
ORGANISM(S): Mus musculus 
2009-04-24 | E-GEOD-4623 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of NCAM-deficient mouse brain
Analysis of brains of mice lacking the neural cell adhesion molecule NCAM (Ncam-/-) in comparison to wild-type mice of same age and genetic background (Ncam+/+). NCAM-deficient mice exhibit deficits in long-term potentiation and spatial learning, as well as increased intermale aggression. We perform...
ORGANISM(S): Mus musculus 
2009-12-01 | E-GEOD-16647 | biostudies-arrayexpress
UnknownChildhood sleep and adolescent chronic fatigue syndrome (CFS/ME): evidence of associations in a UK birth cohort.
Not available
S-EPMC5974860 | biostudies-literature
TranscriptomicsGenome-wide localization of Ino80 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9420 | biostudies-arrayexpress
TranscriptomicsGenome-wide localization of Ino80 and Arp5 on chromosome in Saccharomyces cerevisiae
Background: Chromatin remodeling complexes facilitate the access of enzymes that mediate transcription, replication or repair of DNA by modulating nucleosome position and/or composition. Ino80 is the DNA-dependent Snf2-like ATPase subunit of a complex whose nucleosome remodeling activity requires ac...
ORGANISM(S): Saccharomyces cerevisiae 
2008-04-10 | E-GEOD-9233 | biostudies-arrayexpress
TranscriptomicsIdentification of novel androgen-regulated pathways and mRNA isoforms through genome-wide exon-specific profiling of the LNCaP transcriptome
Androgens drive the onset and progression of prostate cancer (PCa) by modulating androgen receptor (AR) transcriptional activity. Although several microarray-based studies have identified androgen-regulated genes, here we identify in-parallel global androgen-dependent changes in both gene and alter...
ORGANISM(S): Homo sapiens 
2011-12-27 | E-GEOD-32875 | biostudies-arrayexpress
TranscriptomicsExpression profile of telomerase deficient iPSC
Critically short telomeres activate p53-mediated apoptosis, resulting in organ failure and causing malignant transformation. Mutations in genes responsible for telomere maintenance are linked to a number of specific human diseases. We derived induced pluripotent stem cells (iPSCs) from patients with...
ORGANISM(S): Homo sapiens 
2013-02-11 | E-GEOD-42869 | biostudies-arrayexpress
UnknownEvaluation of intestinal biopsy tissue preservation methods to facilitate large-scale mucosal microbiota research.
Not available
S-EPMC11751561 | biostudies-literature
TranscriptomicsIdentification of Cottontail rabbit papillomavirus E2 protein regulated genes
Transcriptome analyses of RNA from C33a cells after induction of CRPV E2 expression by doxycycline C33a cells were established that carry the doxycycline-inducible pRTS-CRPV E2 vector. We analyzed 3 biological replicates (induced/uninduced) using the Affymetrix Human Exon 1.0 ST platform.
ORGANISM(S): Homo sapiens 
2015-03-28 | E-GEOD-67345 | biostudies-arrayexpress
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