Tim-3 - OmicsDI

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1-(4-Aminosulphonylphenyl)-5-(2,4-difluorophenyl)-4,5-dihydro-3-trifluoromethyl-1H-pyrazole (1)
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Department of Functional Sciences, Faculty of Veterinary Medicine, Pharmacology and Toxicology, Fundamental and Applied Research for Animals & Health (FARAH), University of Liège, 4000 Liège 1 (Sart Tilman), Belgium (1)
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Kevin Pagel: Institute of Chemistry and Biochemistry, Freie Universität Berlin, Altensteinstraße 23A, 14195 Berlin, Germany. Fritz Haber Institute of the Max Planck Society, Faradayweg 4‑6, 14195 Berlin, Germany. Philipp Mertins (Philipp.mertins@mdc-berlin.de) : Max Delbrueck Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany. Berlin Institute of Health (BIH), Berlin, Germany. (1)
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protozoa (1)

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microRNA expression in Tim-3 knockdown RAW264.7 cell

RAW264.7 cell was stably transfected with Tim-3 siRNA(SI) or negative control(NC) and were analyzed for microRNA expression Differerently expressed microRNA in Tim-3 knockdown RAW264.7 cells were summarized and were used for further analysis RAW264.7 cells stably transfected with Tim-3 siRNA(SI) o...

ORGANISM(S): Mus musculus

2016-01-14 | E-GEOD-76839 | biostudies-arrayexpress

Expression analysis of Tim-3 knockdown RAW264.7 cell

Investigation of whole genome gene expression level changes in a Tim-3 knockdown RAW264.7 cell, compared to control siRNA transfected RAW264.7 cell. The Tim-3 knockdown of this cell render it hyper-reactive to TLR stimulation. Tim-3 knockdown analyzed in this study are further described in Li Y, Fen...

ORGANISM(S): Mus musculus

2012-12-05 | E-GEOD-42729 | biostudies-arrayexpress

TIM-3 Inhibition Enhances Tumor Progression and Metastasis: A Paradoxical Immune Checkpoint Response

Syngeneic breast tumors were developed by inoculating of 4T1 cells, into the left flank of female Balb/c mice. When tumor volume reached 200-250 mm3, mice were selected randomized way to receive the treatment of anti-TIM-3 monoclonal antibody (mAb) (Clone: RMT3-23, BioXcell, cat. # BE0115, RRID: AB...

ORGANISM(S): Mus musculus (Mouse)

2025-12-29 | PXD065028 | Pride

Expression data from human lymphoma endothelium and reactive lymph node-derived endothelium

Angiogenesis plays a key role in tumor metastasis. Many genes may act in this process including formation of vessels, immune evasion,etc. Different gene expression profiles between lymphoma endothelium cells and reactive lymph node-derived endothelium cells may uncover these genes. And intensive mec...

ORGANISM(S): Homo sapiens

2010-01-14 | E-GEOD-19882 | biostudies-arrayexpress

Role of Tim-3 on tumoral Treg cells

PRJNA591030 | ENA

Gene expression change induced by TIM-3/galectin-9 interaction in primary AML

Analysis of gene expression change after galectin-9 stimulation in primary CD34+TIM-3+ AML cells Total RNA obtained from purified CD34+TIM-3+ primary AML cells with or without recombinant human galectin-9 stimulation (20hrs) was subjected to transcriptome analysis

ORGANISM(S): Homo sapiens

2014-10-10 | E-GEOD-62223 | biostudies-arrayexpress

Transcriptional profile of Tim-3+ and Tim-3- CD8+ T cells from trigeminal ganglion 8 days post HSV-1 infection

PRJNA574060 | ENA

TIM-3 on myeloid cells promotes pulmonary inflammation through increased production of galectin-3

PRJNA1118218 | ENA

Transcription profiling of mouse B16-F10 melanoma cells stimulated with TIM-3

The effect of TIM-3 stimulation was studied on B16F10 mouse melanoma cells, in vitro. Experiment Overall Design: Cy3: B16F10 mouse melanoma cells, treated by unspecific goat IgG (control) for 2 hours. Experiment Overall Design: Cy5: B16F10 mouse melanoma cells, in vitro, treated by an agonist goat p...

ORGANISM(S): Mus musculus

2009-10-15 | E-GEOD-14418 | biostudies-arrayexpress

Immune checkpoint TIM-3 regulates microglia and Alzheimer’s disease [BulkRNAseq_Dataset3_4M]

PRJNA926118 | ENA

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