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TranscriptomicsWhole-genome gene expression profiles of non-tumorous human lung tissues: GRNG set
We profiled genome-wide gene expression in non-tumorous human lung tissues. The overall goal of this project is to improve our molecular understanding of various lung diseases including lung cancer and chronic obstructive pulmonary disease (COPD). Lung specimens were obtained from patients with a va...
ORGANISM(S): Homo sapiens 
2012-06-10 | E-GEOD-23545 | biostudies-arrayexpress
TranscriptomicsA gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK.
BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease consisting of emphysema, small airway obstruction, and/or chronic bronchitis that results in significant loss of lung function over time. METHODS: In order to gain insights into the molecular pathways underlying prog...
ORGANISM(S): Homo sapiens 
2012-09-11 | E-GEOD-27597 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression associated with emphysematous lung destruction
Background: Chronic obstructive pulmonary disease (COPD) is a heterogeneous disease characterized by varying degrees of emphysematous lung destruction and small airway disease, each with distinct effects on clinical outcomes. There is little known about how microRNAs contribute specifically to the e...
ORGANISM(S): Homo sapiens 
2013-12-31 | E-GEOD-49881 | biostudies-arrayexpress
Genomicsena-DATASET-RTL-13-12-2013-10:28:27:441-48 - samples
SCLC - Whole genome sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001000703 | EGA
Genomicsena-DATASET-RTL-02-07-2015-13:42:15:919-50 - samples
SCLC - RNA sequencing data Publication Peifer et al., 2012, Nature Genetics
EGAD00001001431 | EGA
GenomicsSCLC_6.0 - samples
SNP 6.0 arrays of small cell lung cancer
EGAD00010000526 | EGA
GenomicsIntegrative analysis of small cell lung cancer
Small-cell lung cancer (SCLC) is an aggressive lung tumor subtype. We conducted integrated analysis of genome sequencing, transcriptome, and copy number analysis and found an extremely high mutation rate of 7.4±1 protein-changing mutations per million basepairs. Evidence for inactivation of TP53 and...
EGAS00001000299 | EGA
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