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ProteomicsValidation and application of a novel KLK6 activity based probe (IMP2352)
Pancreatic cancer has the lowest survival rate of all common cancers due to late diagnosis and limited treatment options. Serine hydrolases are known to mediate cancer progression and metastasis through initiation of signaling cascades and cleavage of extracellular matrix proteins, and the kallikrei...
ORGANISM(S): Homo sapiens (Human) 
2023-03-10 | PXD035111 | Pride
Abpp Klk Activity-based probe Kallikrein-related peptidase N-terminomics 
ProteomicsEncephalomyocarditis virus protein 2B* antagonises innate immune signalling by interacting with 14-3-3 protein family members_C4PR_LIV
Encephalomyocarditis virus (EMCV) has for decades served as an important model RNA virus. Although most of the EMCV proteins are obtained via proteolytic cleavage of a long polyprotein, 2B* is expressed from a short overlapping open reading frame via an unusual protein-stimulated temporally dependen...
ORGANISM(S): Mesocricetus auratus (Golden hamster) 
2025-08-12 | PXD062303 | Pride
Ap-ms Tmt 2b* Emcv Orbitrap 
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