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ProteomicsBladder cancer tissue-derived exosomes LC-MSMS
To detect the differential expressed proteins in bladder cancer(BCa)-derived exosomes, we isolated BCa tissue-derived exosome and paired normal adjacent tissues (NAT)-derived exosomes. The quantitative proteomics were conducted to detect the upregulated proteins in BCa tissue-derived exosomes compar...
ORGANISM(S): Homo sapiens (Human) 
2025-05-07 | PXD052771 | Pride
Lc-msms Tissue-derived exosomes Bladder cancer 
ProteomicsProteome characterization of mesenchymal stem cells and exosomes
Proteome characterization of mesenchymal stem cells (MSC) and exosomes. MSCs were cultured in normoxic, hypoxic and in presence of FBS. Exosomes were prepared from normoxic and hypoxic conditions.
ORGANISM(S): Homo Sapiens (human) 
2021-04-27 | PXD025584 | JPOST Repository
TranscriptomicsExosomes mediate protective messages during oxidative stress; role of exosomal shuttle RNA
Exosomes are small extracellular nano-vesicles of endocytic origin that mediate different signals between cells, by surface interactions and by shuttling of functional RNA from one cell to another. In this study, we show that exosomes, produced by mouse mast cells exposed to oxidative stress, change...
ORGANISM(S): Mus musculus 
2011-01-07 | E-GEOD-24886 | biostudies-arrayexpress
TranscriptomicsExosomes isolated from M.tb infected cells modulate macrophage response to IFN-gamma
we studied the role of exosomes isolated from M.tb infected macrophages in modulating the macrophage response to IFN-γ. Nimblegen microarray gene expression studies were used to compare the suppression of IFN-γ inducible genes by exosomes relative to the virulent strain of M.tuberculosis. Overall ou...
ORGANISM(S): Mus musculus 
2011-06-05 | E-GEOD-29731 | biostudies-arrayexpress
GenomicsmicroRNA landscape in extracellular vesicles/exosomes derived from bioglass-primed human adipose tissue-derived MSCs
microRNA landscape in extracellular vesicles/exosomes derived from bioglass-primed human adipose tissue-derived MSCs
PRJNA826464 | ENA
ProteomicsComprehensive Proteomic Analysis of Exosomes Derived from Human Bone Marrow-, Adipose Tissue-, and Human Umbilical Cord- Mesenchymal Stem Cells
Mesenchymal stem cells (MSCs)-derived exosomes (exo) have shown comprehensive application prospects over the years. Despite similar functions, exomes from different origins present heterogeneous characteristics and components; however, there are no relevant proteomic analyses. In this study, we isol...
ORGANISM(S): Homo sapiens (Human) 
2021-04-14 | PXD020948 | Pride
Mesenchymal stem cells  exosomes  proteomics  extracellular vesicles  stem cell-based therapy. 
TranscriptomicsmiRNA profiling of rhabdomyosarcoma-derived exosomes compared to donor cells, using the Affymetrix GeneChip miRNA 3.0 array
Exosomes were isolated by differential centrifugation from the fusion negative human embryonal rhabdomyosarcoma (ERMS) cell lines (JR1, Rh36, and RD) and fusion positive alveolar RMS (ARMS) cell lines (Rh30 and Rh41) and characterized by western blot for exosomal markers. miRNA content of the RMS-de...
ORGANISM(S): Homo sapiens 
2016-12-01 | E-MTAB-5321 | biostudies-arrayexpress
ProteomicsBenefits of FAIMS to improve the proteome coverage of hard-to-analyze TMT 10-plex FFPE tissue and plasma-derived exosomes samples
The analysis of complex protein mixtures, such as FFPE tissue or plasma exosomes samples, is a challenge nowadays due to the low proteome coverage achieved by mass spectrometers nowadays. We have here investigated the benefits of FAIMS technology coupled to the Orbitrap Exploris 480 mass spectromete...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD042596 | Pride
Orbitrap exploris 480 Mass spectrometry Proteomics Faims Ffpe tissue Exosomes 
ProteomicsProteomic dataset of exosomes derived from fetal mesenchymal stromal cells
The raw files of the proteomics dataset are N=18 and a brief description of the files is shown below: AF1 raw: exosomes derived from Amniotic Fluid-Mesenchymal Stromal cells 1 AF2.raw: exosomes derived from Amniotic Fluid-Mesenchymal Stromal cells 2 AFA1.raw: exosomes derived from Amniotic Fl...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
MSV000092848 | MassIVE
ProteomicsBenefits of FAIMS to improve the proteome coverage of deteri-orated, and/or cross-linked TMT 10-plex FFPE tissue and plas-ma-derived exosomes samples
The analysis of complex protein mixtures, such as FFPE tissue or plasma exosomes samples, is a challenge nowadays due to the low proteome coverage achieved by mass spectrometers nowadays. We have here investigated the benefits of FAIMS technology coupled to the Orbitrap Exploris 480 mass spectromete...
ORGANISM(S): Homo sapiens (Human) 
2024-01-26 | PXD045362 | Pride
Orbitrap exploris 480 Mass spectrometry Proteomics Faims Ffpe tissue Exosomes 
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