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ProteomicsThe tricuspid valve also maladapts as shown in sheep with biventricular heart failure
Over 1.6 million Americans suffer from significant tricuspid valve leakage. In most cases this leakage is designated as secondary. Thus, valve dysfunction is assumed to be due to valve extrinsic factors. We challenge this paradigm and hypothesize that the tricuspid valve maladapts in those patients ...
ORGANISM(S): Ovis aries 
2021-09-09 | PXD022719 | Pride
Lc-ms/ms Tricuspid valve 
ProteomicsIdentification of Putative Kidney-Derived Proteins in Plasma using Nanoparticle Enrichment
Many diseases, including diabetes and hypertension, can lead to kidney damage, often resulting in long-term health complications and organ failure. Both animal and human studies have documented a causal relationship between high dietary sodium intake and elevated blood pressure. We explored a proteo...
ORGANISM(S): Papio hamadryas 
2026-03-30 | PXD071248 | Pride
Lc-msms Plasma Tissue-leakage proteins Diet challenge Kidney Baboon Non-human primates Sodium Nanoparticle affinity enrichment 
UnknownLow Levels of Factor H Family Proteins During Meningococcal Disease Indicate Systemic Processes Rather Than Specific Depletion by Neisseria meningitidis.
Not available
S-EPMC9204383 | biostudies-literature
GenomicsSerum proteomics of aortic diseases
Aortic diseases are a rare but potentially life-threatening condition. We present a serum proteomic study for a spectrum of aortic diseases including thoracic aortic aneurysms (n = 11), chronic dissections (n = 9), acute aortic dissections (n = 11), and surgically treated dissections (n = 19) as wel...
EGAS00001006201 | EGA
UnknownA superior extracellular matrix binding motif to enhance the regenerative activity and safety of therapeutic proteins.
Not available
S-EPMC10202959 | biostudies-literature
TranscriptomicsExpression data from ozone-treated wild-type and G-protein null mutant Arabidopsis lines
Ozone pollution decreases plant growth and yield worldwide. Some of the effects are genetically-mediated and are reported to involve G-protein signaling pathways. Effects of ozone on gene expression were examined in wild-type and G-protein null mutants to determine affected genes and to determine ...
ORGANISM(S): Arabidopsis thaliana 
2011-12-24 | E-GEOD-34667 | biostudies-arrayexpress
ProteomicsTransplant Model Ischemic Conditioning Causes Tissue Leakage and Suppressed Inflammation in a Porcine Kidney
Background: Remote Ischemic Conditioning (RIC) has been proposed as a therapeutic intervention to circumvent the Ischemia/reperfusion injury (IRI) that is inherent to organ transplantation. Using a porcine kidney transplant model, we aimed to decipher the subclinical molecular effects of a RIC regim...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-04-04 | PXD025273 | Pride
Remote ischaemic conditioning Kidney transplantation Transcriptomics Inflammation Proteomics Integrative omics 
TranscriptomicsBlockade of Endothelin Receptors Mitigates SARS-CoV-2-induced Osteochondral Damage
Previous studies have detected the presence of SARS-CoV-2 viral proteins in bronchial cartilage chondrocytes. We hypothesised that the leakage of viral proteins to local joint tissue was due to virus-induced endothelial dysfunction. Studies have also shown upregulation of endothelin-1 (ET-1), the mo...
ORGANISM(S): Homo sapiens 
2024-05-08 | GSE267009 | GEO
UnknownGeneration of the Ci1 Reporter Mouse Strain with Enhanced Fluorescence for Tissue Clearing Applications.
Not available
S-EPMC12314181 | biostudies-literature
UnknownStromal regulation of vessel stability by MMP14 and TGFbeta.
Not available
S-EPMC2860851 | biostudies-literature
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