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TranscriptomicsInvestigation of Alterations in Gene Expression in the Retina Induced by Intravitreal Injection of titanium dioxide nanoparticles
In this study, we investigated the safety of locally delivered titanium dioxide nanoaprticles at the level of gene expression in the retina. To figure out any definite dose-dependent effect, we injected titanium dioxide nanoparticles into the vitreous cavity of 8-week-old male C57BL/6 mice at the co...
ORGANISM(S): Mus musculus 
2013-07-20 | E-GEOD-49048 | biostudies-arrayexpress
TranscriptomicsEffect of Titanium dioxide nanoparticles on Escherichia coli K12 MG1655 genes expression
In the present study, we investigated the transcriptional expression patterns of the model strain E. coli exposed to titanium dioxide nanoparticles (NP-TiO2), under dark conditions by using a microarray. Expression profiles were compared to unexposed E.coli and ratio of expression were analysed. Cel...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2014-09-08 | E-GEOD-55972 | biostudies-arrayexpress
ProteomicsMolecular responses of alveolar epithelial A549 cells to chronic exposure to titanium dioxide nanoparticles: a proteomic view
Although the biological effects of titanium dioxide nanoparticles (TiO2-NPs) have been studied for more than two decades, the mechanisms governing their toxicity are still unclear. We applied 2D-gel proteomics analysis on A549 epithelial alveolar cells chronically exposed for 2 months to 2.5 or 50 µ...
ORGANISM(S): Homo sapiens (Human) 
2015-08-24 | PXD002662 | Pride
Titanium dioxide nanoparticles 2d gel electrophoresis Nanolc-ms/ms 
TranscriptomicsTitanium dioxide nanoparticles exposure
This project utilized oligonucleotide microarrays to examine gene expression patterns in adult male fathead minnows (Pimephales promelas) exposed to a common nanomaterial, titanium dioxide (TiO2, stearate-coated particles, MT-100TV®). We exposed adult male fathead minnows for 96 hr to three doses (...
ORGANISM(S): Pimephales promelas 
2010-12-22 | E-GEOD-17902 | biostudies-arrayexpress
TranscriptomicsExpression data from 29-day old Arabidopsis plants
Metal oxide engineered nanoparticles, which are widely used in diverse applications, are known to impact terrestrial plants. These nanoparticles have a potential to induce changes in plant tissue transcriptomes, and thereby the productivity. Here we looked at how the two commonly used nanoparticles...
ORGANISM(S): Arabidopsis thaliana 
2016-05-31 | E-GEOD-80461 | biostudies-arrayexpress
TranscriptomicsDietary titanium dioxide (E171) increases systemic ROS levels and alters the colon transcriptome – Evidence from a human dietary intervention study
This study provides critical insights into the adverse effects of titanium dioxide (E171) on human gastrointestinal health and its potential molecular mechanisms of action, marking a significant advancement in food toxicology. Through a human dietary intervention study involving 31 participants cons...
ORGANISM(S): Homo sapiens 
2025-09-30 | E-MTAB-15089 | biostudies-arrayexpress
UnknownCharacterization of Food-Additive Titanium Dioxide and Dietary Exposure to Titanium Dioxide Nanoparticles among the Chinese Population.
Not available
S-EPMC11397697 | biostudies-literature
TranscriptomicsExpression data from 12-day old Arabidopsis germinants
Seed germination of a terrestrial plant constitute dynamic changes in various physiological processes related to growth and development. These physiological processes can be affected by various abiotic and biotic stressors. Here we looked at how the two commonly used nanoparticles, nano-titania (TiO...
ORGANISM(S): Arabidopsis thaliana 
2014-07-29 | E-GEOD-59809 | biostudies-arrayexpress
TranscriptomicsEffect of Titanium dioxide nanoparticles on Escherichia coli K12 MG1655 genes expression
In the present study, we investigated the transcriptional expression patterns of the model strain E. coli exposed to titanium dioxide nanoparticles (NP-TiO2), under dark conditions by using a microarray. Expression profiles were compared to unexposed E.coli and ratio of expression were analysed.
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 Escherichia coli CFT073 Escherichia coli O157:H7 str. Sakai Escherichia coli O157:H7 str. EDL933 
2014-09-08 | GSE55972 | GEO
ProteomicsHuman serum proteome interaction of titanium dioxide nanoparticles (TiO2-NPs)
The present study aimed to investigate the human serum proteome wide interaction of titanium dioxide nanoparticles (TiO2-NPs). Methodologically, the specific interaction of serum proteins with TiO2-NPs were explored through high resolution proteomic profiling. Here we employed LC-MS/MS based HRMS pr...
ORGANISM(S): Homo Sapiens 
2024-11-12 | PXD057816 |
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