Tjokrodirijo Rayman T N RTN

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Proteomics (3)
Metabolomics (1)

Organisms

Homo sapiens (3)
Legionella pneumophila subsp. pneumophila Lp02 (1)

Repository

pride (3)
MetaboLights (1)

Tissue

Cell culture (1)
HeLa cell (1)

Technology Type

Bottom-up proteomics (3)
Mass Spectrometry (3)
Mass spectrometry (1)

Instrument Platform

Flow injection analysis MS - negative (1)

Publication Date

2024 (2)
2025 (2)

CHEBI ID

CHEBI:74309; HMDB0062518; HMDB62518 (1)
CHEBI:133815; HMDB0030856; HMDB0040140; HMDB30856; HMDB40140 (1)
CHEBI:63334; HMDB0015414; HMDB15414 (1)
CHEBI:89499; HMDB0002522; HMDB0002586; HMDB0002642; HMDB02522; HMDB02586; HMDB02642 (1)
CHEBI:239286; HMDB0015200; HMDB15200 (1)
CHEBI:85165; HMDB0062591; HMDB62591 (1)
CHEBI:85166; HMDB0013043; HMDB0013045; HMDB0013653; HMDB0062663; HMDB13043; HMDB13044; HMDB13045; HMDB13653; HMDB62663 (1)
CHEBI:775715; HMDB0015648; HMDB15648 (1)
CHEBI:63818; HMDB0062325; HMDB62325 (1)
CHEBI:71169; HMDB0000912; HMDB00912 (1)
CHEBI:84634; HMDB0005066; HMDB05066 (1)
CHEBI:48983; HMDB0032717; HMDB0033437; HMDB32717; HMDB33437 (1)
CHEBI:479320; HMDB0013308; HMDB0062338; HMDB13308; HMDB62338 (1)
CHEBI:479286; HMDB0013631; HMDB13631 (1)
CHEBI:51164; HMDB0014727; HMDB14727 (1)
CHEBI:50091; HMDB0004645; HMDB04645 (1)
CHEBI:70811; HMDB0013240; HMDB13240 (1)
CHEBI:132607; HMDB0030555; HMDB0094679; HMDB30555; HMDB94679 (1)
CHEBI:58592; HMDB0034765; HMDB0034768; HMDB0038636; HMDB0062575; HMDB34765; HMDB34768; HMDB38636; HMDB62575 (1)
CHEBI:110179; CHEBI:132606; HMDB0030767; HMDB0037774; HMDB0037775; HMDB0094645; HMDB30767; HMDB37774; HMDB37775; HMDB94645 (1)
CHEBI:61313; HMDB0005943; HMDB0040180; HMDB05943; HMDB40180 (1)
CHEBI:385866; HMDB0000706; HMDB0011167; HMDB0028760; HMDB0028991; HMDB00706; HMDB06113; HMDB11167; HMDB28760; HMDB28991 (1)
CHEBI:74303; HMDB0013238; HMDB13238 (1)
CHEBI:417823; HMDB0030965; HMDB0037517; HMDB30965; HMDB37517 (1)
CHEBI:82944; HMDB0062550; HMDB62550 (1)
CHEBI:68433; CHEBI:68434; CHEBI:73506; HMDB0011170; HMDB0011171; HMDB0028822; HMDB0028823; HMDB0029152; HMDB0029153; HMDB11170; HMDB11171; HMDB28822; HMDB28823; HMDB29152; HMDB29153 (1)
CHEBI:70749; CHEBI:84834; HMDB0000705; HMDB0000756; HMDB00705; HMDB00756 (1)
CHEBI:87428; HMDB0031061; HMDB0059866; HMDB0061657; HMDB31061; HMDB59866; HMDB61657 (1)
CHEBI:20607; HMDB0000982; HMDB0039229; HMDB00982; HMDB39229 (1)
CHEBI:17976; HMDB0033197; HMDB0036047; HMDB0059661; HMDB33197; HMDB36047; HMDB59661 (1)

Metabolite Name

CDP-DG(18:2(9Z,11Z)/a-17:0) (1)
Pentadecanoyl-CoA (1)
Ophiopogonin C'' (1)
DSLET (1)
6''''-Malonylapiin (1)
(5-{4-[2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-3,4-dihydro-2H-1-benzopyran... (1)
Myricetin 7-(6''''-galloylglucoside) (1)
(R)-6''-O-(4-Geranyloxy-2-hydroxycinnamoyl)-marmin (1)
Sultamicillin tosilate (1)
6-{3-[6-(3,4-dihydroxy-6-methyl-5-oxooxan-2-yl)-5,7-dihydroxy-4-oxo-4H-chro... (1)
[(6-{[5,7-dihydroxy-2-(4-oxocyclohexa-2,5-dien-1-ylidene)-2H-chromen-3-yl]o... (1)
3,3''-Bis(4''''-hydroxyanigorufone) (1)
({3,4,5-trihydroxy-6-[3,5,7-trihydroxy-2-(2,4,5-trihydroxyphenyl)-3,4-dihyd... (1)
4-{[4-(Diethylamino)phenyl](2,4-disulfophenyl)methylene}-N,N-diethyl-2,5-cy... (1)
1-Phosphatidyl-1D-myo-inositol 3,4-bisphosphate (1)
6-(2-{8,8-dimethyl-2-oxo-2H,8H-pyrano[2,3-f]chromen-3-yl}-5-methoxyphenoxy)... (1)
6-(2,4-dihydroxyphenyl)-2-{3-[3-(2,4-dihydroxyphenyl)propanoyl]-2,6-dihydro... (1)
Provincialin; NPC (1)
3,4,5-trihydroxy-6-{4-[1-hydroxy-3-(5-methoxy-2,2-dimethyl-2H-chromen-6-yl)... (1)
3,4,5-trihydroxy-6-({15-hydroxy-11-methoxy-13-oxo-6,8,20-trioxapentacyclo[1... (1)
(7''R,8''R)-4,7''-Epoxy-3''-methoxy-4'',5,9,9''-lignanetetrol 9''-glucoside (1)
(4-{3-[2,4-dihydroxy-5-(3-methylbut-2-en-1-yl)phenyl]-2-hydroxy-3-oxopropyl... (1)
8-(2-{[(2E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]oxy}propan-2-yl)-2-oxo-2H,8... (1)
2-(2,4-dihydroxyphenyl)-3-(3,7-dimethylocta-2,6-dien-1-yl)-5,7-dihydroxy-6-... (1)
13-Hydroxy-5''-O-methylmelledonal (1)
Vindoline; 1-Lyso-2-arachidonoyl-phosphatidate (1)
[(4-{5,14-dihydroxy-3-methoxy-8,17-dioxatetracyclo[8.7.0.0ï¿½ï¿½,ï¿½ï¿½ï¿½.0ï¿ (1)
2-{3-[(6-carboxy-3,4,5-trihydroxyoxan-2-yl)oxy]phenyl}-3,5,7-trihydroxy-1ï¿½ï¿ (1)
Ponceau MX (1)
N-Ethylmaleimide-S-glutathione (1)

Lab affiliation

Head Proteomics Group , Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (1)
Head Proteomics Group, Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (1)
Head Proteomics Group, Leiden University Medical Center, Center for Proteomics and Metabolomics, PO Box 9600, Postal zone P1-Q, 2300 RC Leiden, The Netherlands (1)

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AMPK activation induces RALDH+ tolerogenic dendritic cells by rewiring glucose and lipid metabolism.

Dendritic cell (DC) activation and function are underpinned by profound changes in cellular metabolism. Several studies indicate that the ability of DCs to promote tolerance is dependent on catabolic metabolism. Yet the contribution of AMP-activated kinase (AMPK), a central energy sensor promoting c...

2024-08-16 | MTBLS10647 | MetaboLights

Immunopeptidomics analysis of human atherosclerosis plaques identifies antigenic drivers of atherosclerosis

Atherosclerosis has an auto-immune component driven by self-reactive T and B cells. Identifying their antigenic drivers may lead to new diagnosis and treatment approaches. Here, we aim to identify immunogenic T cell epitopes derived from atherosclerosis-relevant proteins such as ApoB100 by studying ...

ORGANISM(S): Homo sapiens (Human)

2025-09-18 | PXD068446 | Pride

Development of covalent probes to capture Legionella pneumophila effector enzymes

Upon infection of host cells Legionella pneumophila releases a multitude of effector enzymes into the hosts cytoplasm that hijack a plethora of cellular activities, including the hosts ubiquitination pathways. Effectors belonging to the SidE-family are involved in non-canonical serine phosphoribosyl...

ORGANISM(S): Homo sapiens (Human) Legionella pneumophila subsp. pneumophila Lp02

2025-05-06 | PXD049797 | Pride

Legionella pneumophila Activity-based probe Ubiquitylation Adp-ribosylation Bacterial infection

Development of inhibitors, probes, and PROTAC provides a complete toolbox to study PARK7 in the living cell

The innovation of combined chemical tools, such as small molecule inhibitors, activity-based probes (ABPs), and proteolysis targeting chimeras (PROTACs) for a specific target, not only advances clinical drug discovery but also provides a chemical toolbox to study the diverse biological perspective o...