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UnknownGetting to the heart of stem cell research: an interview with Christine Mummery.
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S-EPMC10233713 | biostudies-literature
MetabolomicsMetabolomic profiling of Fraxinus excelsior genotypes tolerant or susceptible to ash dieback disease reveals changes in iridoid glycosides
European common ash, Fraxinus excelsior L., is currently threatened by Ash dieback (ADB) caused by the fungus, Hymenoscyphus fraxineus. To detect and identify metabolites that may be products of pathways important in contributing to resistance against H. fraxineus we performed untargeted metabolomic...
2016-11-09 | MTBLS372 | MetaboLights
TranscriptomicsPBMC response to B. pertussis filamentous hemagglutinin stimulation in vitro
Filamentous hemagglutinin (FHA), Bordetella pertussis' key adhesin, is both present at the cell surface and released in the extracellular milieu. To comprehend the role free FHA plays in the pathogenic process, we analyzed the global transcriptional changes in human peripheral blood mononuclear cell...
ORGANISM(S): Homo sapiens 
2008-10-29 | E-GEOD-8802 | biostudies-arrayexpress
MetabolomicsA multiplatform metabolomic approach to characterize fecal signatures of stressful postnatal events in chicks: a pilot study
Negative experiences in early life can induce long-lasting effects on the welfare, health, and performance of farm animals. A delayed placement of chicks in breeding houses has negative effects on their performance, and results in fecal-specific odours detectable by rats. Based on this observation, ...
2019-04-11 | MTBLS763 | MetaboLights
MetabolomicsA metabolic dependency of EBV can be targeted to hinder B cell transformation

Following infection of B cells, Epstein Barr virus (EBV) engages host pathways that mediate cell proliferation and transformation, contributing to the propensity of the virus to drive immune dysregulation and lymphomagenesis. We found that the EBV protein EBNA2 initiates NAD de novo bios...

2024-04-29 | MTBLS2243 | MetaboLights
TranscriptomicsRNA-seq of different tissues from wild-type and C/EBPα ΔuORF mutant African turquoise killifish Nothobranchius furzeri
The transcription factor CCAAT/enhancer binding protein alpha (C/EBPα) regulates cell differentiation, proliferation, and function in various tissues, including the liver, adipose tissue, skin, lung, and hematopoietic system. Studies in rats, mice, humans, and chickens have shown that CEBPA mRNA und...
ORGANISM(S): Nothobranchius furzeri 
2026-05-26 | E-MTAB-15325 | biostudies-arrayexpress
TranscriptomicsResponse of Rhodopirellula baltica to heat shock
Expression profiling of the stress response of the marine Planctomycete Rhodopirellula baltica after a temperature up-shift. R. baltica cultures were grown at 28°C and then shifted to 37°C. Samples were taken after 10, 20, 40, 60 and 300min and compared with cultures before the up-shift (28°C). Tim...
ORGANISM(S): Rhodopirellula baltica 
2009-09-09 | E-GEOD-13769 | biostudies-arrayexpress
ProteomicsProteomic profiling of Palbociclib arrested cells ± APC/C inactivation.
Cellular proliferation is highly regulated to ensure proper tissue homeostasis and to prevent diseases such as cancer. In actively proliferating cells, entry into S phase of the cell cycle and initiation of DNA replication is promoted by inactivation of the E3 ubiquitin ligase APC/C (anaphase promot...
ORGANISM(S): Homo sapiens (Human) 
2024-07-18 | PXD046783 | Pride
Cancer Palbociclib Cell cycle Apc/c 
TranscriptomicsResponse of Rhodopirellula baltica to salt shift
Expression profiling of the stress response of the marine Planctomycete Rhodopirellula baltica after a salinity up-shift. R. baltica cultures were grown at 28°C in mineral media with 17.5% salinity and up-shifted to 59.9%. Samples were taken after 10, 20, 40, 60 and 300min and compared with culture...
ORGANISM(S): Rhodopirellula baltica 
2010-05-05 | E-GEOD-14075 | biostudies-arrayexpress
Genomics4DNESB7XYI9V - sci-Hi-C on mESCs differentiated to embryoid body
4DNESB7XYI9V - sci-Hi-C on mESCs differentiated to embryoid body
PRJNA770075 | ENA
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