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GenomicsMesotoga sp. TolDC
Mesotoga sp. TolDC Genome sequencing and assembly
PRJNA215414 | ENA
TranscriptomicsRNA-seq analysis of human T CD4+ cells after their interaction with autologous antigen-specific vitamin D3-generated tolerogenic dendritic cells
The use of autologous tolerogenic dendritic cells (tolDC) has become a promising alternative for the treatment of autoimmune diseases. Among the different alternatives available, the use of vitamin D3 for the generation of tolDC (vitD3‑tolDC) constitutes one of the most robust approaches due to thei...
ORGANISM(S): Homo sapiens 
2020-12-21 | GSE128816 | GEO
GenomicsExpression data (HG-U133 Plus 2.0) from human monocyte-derived cell types (TolDC, M-MDSC, MoDC)
Expression data (HG-U133 Plus 2.0) from human monocyte-derived cell types (TolDC, M-MDSC, MoDC)
PRJNA756575 | ENA
TranscriptomicsHuman tolerogenic dendritic cell subtypes exert divergent effects on induction of cytotoxic CD4+ T cells
Tolerogenic dendritic cells (tolDC) are currently in clinical trials for the treatment of autoimmune diseases such as rheumatoid arthritis and multiple sclerosis. The methods for producing therapeutic tolDC vary widely, with little being known about the commonalities and differences of distinct cell...
ORGANISM(S): Homo sapiens 
2025-12-20 | GSE313751 | GEO
ProteomicsMyeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways
Understanding the molecular mechanisms that initiate and control immunosuppression by myeloid cells is essential to overcoming the myeloid-induced disbalance of the immune system observed in patients. Myeloid cells are implicated in aggravated suppression of immunity as seen in cancer as well as in ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-20 | PXD027715 | Pride
Human Mdscs Modc Fasp Hnscc Toldc Monocytes 
TranscriptomicsMicroarray of tolerogenic dendritic cells differentiated in the presence of vitamin D3, dexamethasone or rapamycin
The comparative analysis of the transcriptome of tolerogenic dendritic cells (tolDC) differentiated using different stimulus (either vitamin D3, dexamethasone or rapamycin) would allow to evidence potential common genes and pathways that could explain their potency as tolerance-inducing cells.
ORGANISM(S): Homo sapiens 
2018-07-31 | E-MTAB-6937 | biostudies-arrayexpress
UnknownComparative transcriptomic profile of tolerogenic dendritic cells differentiated with vitamin D3, dexamethasone and rapamycin.
Not available
S-EPMC6175832 | biostudies-literature
UnknownCombined Therapy of Vitamin D3-Tolerogenic Dendritic Cells and Interferon-β in a Preclinical Model of Multiple Sclerosis.
Not available
S-EPMC8698295 | biostudies-literature
UnknownTolerogenic dendritic cells induced by BD750 ameliorate proinflammatory T cell responses and experimental autoimmune encephalitis in mice.
Not available
S-EPMC5630474 | biostudies-literature
UnknownTranscriptomic Analysis Identifies A Tolerogenic Dendritic Cell Signature.
Not available
S-EPMC8564488 | biostudies-literature
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