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TranscriptomicsTolerogenic dendritic cells protect against acute kidney injury
We use tolDCs from syngeneic (C57BL6) and allogeneic (BALB/c) mice to show potent renoprotective abilities in a ischemia reperfusion AKI model. Dendritic cells were derived from mice bone marrow and cultured for 7 days with GM-CSF and IL-4. Tolerogenic DCs were cultured in the same DC media but with...
ORGANISM(S): Mus musculus 
2024-11-25 | E-MTAB-14618 | biostudies-arrayexpress
GenomicsTolerogenic dendritic cells protect against acute kidney injury
Tolerogenic dendritic cells protect against acute kidney injury
PRJNA844376 | ENA
ProteomicsMyeloid-derived suppressor cells and tolerogenic dendritic cells are distinctively induced by PI3K and Wnt signaling pathways
Understanding the molecular mechanisms that initiate and control immunosuppression by myeloid cells is essential to overcoming the myeloid-induced disbalance of the immune system observed in patients. Myeloid cells are implicated in aggravated suppression of immunity as seen in cancer as well as in ...
ORGANISM(S): Homo sapiens (Human) 
2023-09-20 | PXD027715 | Pride
Human Mdscs Modc Fasp Hnscc Toldc Monocytes 
GenomicsTolerogenic dendritic cells protect against acute kidney injury
Tolerogenic dendritic cells protect against acute kidney injury
PRJEB82756 | ENA
GenomicsGeneration of Induced Pluripotent Stem Cells Derived Tolerogenic Dendritic Cells and Their Immunosuppressive Properties.
Generation of Induced Pluripotent Stem Cells Derived Tolerogenic Dendritic Cells and Their Immunosuppressive Properties.
PRJNA1314695 | ENA
GenomicsA genome-wide CRISPR Screen identifies targets that drive Tolerogenic Dendritic Cells
A genome-wide CRISPR Screen identifies targets that drive Tolerogenic Dendritic Cells
PRJNA1532465 | ENA
UnknownProtocol of generation of tolerogenic dendritic cells affects their transcriptional and metabolic profiles leading to specific tolerogenic functions.
Not available
S-EPMC12589953 | biostudies-literature
TranscriptomicsGeneration of Induced Pluripotent Stem Cells Derived Tolerogenic Dendritic Cells and Their Immunosuppressive Properties.
Background: Dendritic cells (DCs), the primary antigen-presenting cells, regulate immune priming. DCs with a semi-mature phenotype and tolerogenic properties, termed tolerogenic DCs (tolDCs), are promising candidates for cell therapy to induce immune tolerance. Induced pluripotent stem cells (iPSCs)...
ORGANISM(S): Homo sapiens 
2026-03-19 | GSE307178 | GEO
GenomicsDimethyl Fumarate Restores Functional Vitamin-D3 Tolerogenic Dendritic Cells differentiated from Multiple Sclerosis Patients
Dimethyl Fumarate Restores Functional Vitamin-D3 Tolerogenic Dendritic Cells differentiated from Multiple Sclerosis Patients
PRJNA1111870 | ENA
UnknownTargeting aryl hydrocarbon receptor functionally restores tolerogenic dendritic cells derived from patients with multiple sclerosis.
Not available
S-EPMC11527446 | biostudies-literature
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