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ProteomicsPcbp1 blocks MEK/ERK signaling and facilitate Naïve to Primed pluripotency
Embryonic stem cells (ESCs) represent a unique cell type that is characterized by the ability to self-renew and differentiate into all types of somatic cells, as well as into germ cells. An understanding of the mechanisms which underlie their functioning is necessary for their usage in regenerative ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-04 | PXD039287 | Pride
Pluripotency Pcbp1 Timstof pro Embryonic stem cells Mek/erk signaling 
TranscriptomicsActivation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. doi: 10.1038/nm.4109
The multiple claims about reactivation of the embryonic stem cell (ESC) pluripotency factor OCT4 in somatic cells are highly controversial due to the fact that there is no direct evidence that OCT4 has a functional role in cells other than ESCs. Herein we demonstrate that smooth muscle cell (SMC)-sp...
ORGANISM(S): Mus musculus 
2016-05-15 | E-GEOD-75044 | biostudies-arrayexpress
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