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TranscriptomicsThe Poly(C) binding protein Pcbp2, and its retrotransposed derivative Pcbp1, are independently essential to mouse development
RNA-binding proteins participate in a complex array of post-transcriptional controls essential to cell-type specification and somatic development. Despite their detailed biochemical characterizations, the degree to which each RNA-binding protein impacts on mammalian embryonic development remains in...
ORGANISM(S): Mus musculus 
2015-11-05 | E-GEOD-72491 | biostudies-arrayexpress
ProteomicsLC-MSMS validation of LtpM-mediated O-Glc modification of purified LtpM, CUGBP1, PCBP1 and PCBP2
Validation of LtpM autoglucosylation; validation of the identified O-Glc-modified proteins (CUGBP1, PCBP1 and PCBP2)
ORGANISM(S): Legionella pneumophila Homo sapiens (Human) 
2025-07-14 | PXD058433 | Pride
Ltpm Lc-msms 
ProteomicsASF1B promotes gastric cancer liver metastasis through inhibiting ZDHHC9/PCBP1/ SLC7A11 signaling axis mediated ferroptosis
Despite advances in comprehensive gastric cancer (GC) therapies, the prognosis of patients with liver metastasis remains poor. Identifying potential molecular targets for GC liver metastasis (GCLM) may provide new treatment avenues. Initially, clinical samples from patients with GCLM were analyzed t...
ORGANISM(S): Homo Sapiens 
PXD069269 |
GenomicsPCBP1 regulates transcription by binding ssDNA at promoters
PCBP1 regulates transcription by binding ssDNA at promoters
PRJNA936868 | ENA
ProteomicsPcbp1 blocks MEK/ERK signaling and facilitate Naïve to Primed pluripotency
Embryonic stem cells (ESCs) represent a unique cell type that is characterized by the ability to self-renew and differentiate into all types of somatic cells, as well as into germ cells. An understanding of the mechanisms which underlie their functioning is necessary for their usage in regenerative ...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-04 | PXD039287 | Pride
Pluripotency Pcbp1 Timstof pro Embryonic stem cells Mek/erk signaling 
ProteomicsPCBP1 regulates aberrant alternative splicing of AARS2 in congenital cardiomyopathy
Alanyl-transfer RNA synthetase 2 (AARS2) is a nuclear encoded mitochondrial tRNA synthetase that is responsible for charging of tRNA-Ala with alanine during mitochondrial translation. Homozygous or compound heterozygous mutations in the Aars2 gene, including those affecting its splicing, are linked ...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-16 | PXD057114 | Pride
UnknownlncRNA PCBP1-AS1 Aggravates the Progression of Hepatocellular Carcinoma via Regulating PCBP1/PRL-3/AKT Pathway.
Not available
S-EPMC7352448 | biostudies-literature
GenomicsTranscriptome of embryonic hearts with cardiomyocyte-specific deficiency of Pcbp1
Transcriptome of embryonic hearts with cardiomyocyte-specific deficiency of Pcbp1
PRJNA1169902 | ENA
GenomicsmRNA sequencing of human AC16 cells expressing PCBP1, PCBP2, or both
mRNA sequencing of human AC16 cells expressing PCBP1, PCBP2, or both
PRJNA1295936 | ENA
GenomicsAlcohol Withdrawal Is Associated with Altered PCBP1 RNA Binding in the Hippocampus
Alcohol Withdrawal Is Associated with Altered PCBP1 RNA Binding in the Hippocampus
PRJNA1472068 | ENA
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