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UnknownA modified formulation of Huanglian-Jie-Du-Tang reduces memory impairments and β-amyloid plaques in a triple transgenic mouse model of Alzheimer's disease.
Not available
S-EPMC5524904 | biostudies-literature
UnknownTreatment Effects of Ischemic Stroke by Berberine, Baicalin, and Jasminoidin from Huang-Lian-Jie-Du-Decoction (HLJDD) Explored by an Integrated Metabolomics Approach.
Not available
S-EPMC5574319 | biostudies-literature
ProteomicsProteomic characterization of native and decellularized rat submandibular gland scaffolds prepared using the S3T1 protocol
Salivary gland hypofunction lacks effective regenerative treatment, and organ-specific decellularized extracellular matrix scaffolds represent a promising biomaterial platform for tissue engineering. In this study, rat submandibular glands were decellularized using a rapid S3T1 workflow consisting o...
ORGANISM(S): Rattus norvegicus (Rat) 
2026-04-21 | PXD077315 | Pride
Extracellular matrix scaffold Proteomics Dia Rat Submandibular gland Salivary gland tissue engineering Decellularization Lc-ms/ms 
MetabolomicsMicrobiome and metabolome features in inflammatory bowel disease via multi-omics integration analyses across cohorts

The perturbations of the gut microbiota and metabolites are closely associated with the progression of inflammatory bowel disease (IBD). However, inconsistent findings across studies impede a comprehensive understanding of their roles in IBD and their potential as reliable diagnostic biomarkers. ...

2026-01-28 | MTBLS8713 | MetaboLights
ProteomicsProteomic analysis in mouse liver
Protein SUMOylation is crucial in both physiological and pathological contexts, but its role in acute liver injury is poorly understood. We found that SENP3, a SUMO2/3 protease, rapidly accumulates in hepatocytes around the pericentral vein zone within 2 hours of CCl₄-induced liver injury in mice. K...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD065391 | Pride
Proteomic  senp3  liver 
ProteomicsSUMOylation proteomic analysis in mouse liver
Protein SUMOylation is crucial in both physiological and pathological contexts, but its role in acute liver injury is poorly understood. We found that SENP3, a SUMO2/3 protease, rapidly accumulates in hepatocytes around the pericentral vein zone within 2 hours of CCl₄-induced liver injury in mice. K...
ORGANISM(S): Mus musculus (Mouse) 
2026-02-09 | PXD065419 | Pride
Senp3 Protein sumoylation Liver 
UnknownRandomized phase III trial of induction chemotherapy with docetaxel, cisplatin, and fluorouracil followed by surgery versus up-front surgery in locally advanced resectable oral squamous cell carcinoma.
Not available
S-EPMC5569675 | biostudies-literature
ProteomicsMulti-omics Analysis Shed Light on the Extracellular Role of PCMT1
Proteins are constantly damaged by intracellular and extracellular factors, particularly under stress conditions, leading to an accumulation of modified proteins like isoaspartate (isoD), which is linked to aging and various diseases. The repair enzyme PCMT1 (Protein-L-isoaspartate O-methyltransfera...
ORGANISM(S): Mus musculus (Mouse) 
2025-06-16 | PXD058971 | Pride
Pcmt1  multi-omics  isoaspartate  extracellular  stress condition 
UnknownGlobal trends in indocyanine green fluorescence navigation in the field of gastric cancer: bibliometrics and knowledge atlas analysis.
Not available
S-EPMC10585495 | biostudies-literature
UnknownHigh extracellular matrix stiffness upregulates TNNT1 to awaken dormant tumor cells in liver metastatic niches of gastric cancer.
Not available
S-EPMC12119719 | biostudies-literature
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