Sort   by:  
 Page size 
TranscriptomicsOral tongue cancer gene expression profiling: Identification of novel potential prognosticators
Background: The present study is aimed at identifying potential candidate genes as prognostic markers in human oral tongue squamous cell carcinoma (SCC) by large scale gene expression profiling. Methods: The gene expression profile of patients (n=37) with oral tongue SCC were analyzed using Affyme...
ORGANISM(S): Homo sapiens 
2008-11-14 | E-GEOD-13601 | biostudies-arrayexpress
ProteomicsIntegrated proteomics and phosphoproteomics revealed druggable kinases in neoadjuvant chemotherapy resistant tongue cancer
Tongue squamous cell carcinoma is characterised by poor prognosis and high metastatic events. Patients with unresectable tumors are benefiting from neoadjuvant chemotherapy (NACT) which surgical resection, and controls distant metastasis, and locoregional recurrence. However, resistance to NACT limi...
ORGANISM(S): Homo sapiens (Human) 
2023-03-11 | PXD037356 | Pride
Human Lc-msms Tissue Tongue 
MetabolomicsIdentification and Validation of Plasma Lipid Biomarkers for Oral Cancer Diagnosis

Despite lipid metabolic changes in oral cancer (OC), their potential as diagnostic markers remains unclear. This study assessed the diagnostic potential of metabolites for OC detection. Plasma metabolites of patients with OC and healthy controls (HC) were profiled using untargeted and targeted me...

2026-05-02 | MTBLS12655 | MetaboLights
TranscriptomicsHSC-3 cells (control) vs. HSC-3-5 cells [tongue]
HSC-3-5 cells, which drived from human HSC-3 cells via transwell invasion assay was high invasive.Tumor cells were injected into the tongue of SCID mice. After 1 week, transcriptional profiling of human HSC-3 tumor comparing with high invasive HSC-3-5 tumor. Goal was to determine the effects of inv...
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-39725 | biostudies-arrayexpress
GenomicsWhole Genome Sequencing of Tongue cancer samples and cell line
Whole genome sequencing (WGS) of tongue cancer samples and cell line was performed to identify the fusion gene translocation breakpoint. WGS raw data was aligned to human reference genome (GRCh38.p12) using BWA-MEM (v0.7.17). The BAM files generated were further analysed using SvABA (v1.1.3) tool to...
ORGANISM(S): Homo sapiens 
2024-02-17 | E-MTAB-12534 | biostudies-arrayexpress
TranscriptomicsPARVB overexpression increases migration capability and defines high risks for endophytic growth and metastasis in tongue squamous cell carcinoma.
Tongue squamous cell carcinoma (TSCC) varies in characteristics even in early stages and is mainly classified into three subtypes, which are superficial, exophytic and endophytic types, based on a macroscopic appearance of tumor growth.Of these subtypes, endophytic tumor has a poorer prognosis becau...
ORGANISM(S): Homo sapiens 
2015-12-31 | E-GEOD-52915 | biostudies-arrayexpress
MetabolomicsBiomarker Discovery in Oral Cancer (OSMF & OSCC) and its severity

Oral squamous cell carcinoma (OSCC) is frequently the outcome of oral submucous fibrosis (OSMF), a common possibly premalignant disease. In our study, a cohort of 50 patients with OSCC and OSMF, along with 50 healthy controls, was analyzed to identify significant metabolic differences between the...

2024-10-23 | MTBLS11009 | MetaboLights
TranscriptomicsDiverse routes to oral cancer differing in genome instability and risk for cervical node metastasis
Clinically evident oral lesions, oral epithelial dysplasia, precede development of oral squamous cell carcinomas (SCC) and are considered to transform to cancer by acquisition of genetic or epigenetic alterations. Here, we show that, +3q24-qter, -8pter-p23.1, +8q12-q24.2 and +20 are early events id...
ORGANISM(S): Homo sapiens 
2011-11-18 | E-GEOD-28407 | biostudies-arrayexpress
GenomicsTranscriptome sequencing in patients with tongue cancer
Transcriptome sequencing in patients with tongue cancer
PRJNA602314 | ENA
TranscriptomicsGene expression profiling of archival tongue carcinoma and normal tongue tissue
This SuperSeries is composed of the following subset Series: GSE34105: Gene expression profiling of archival tongue carcinoma and normal tongue tissue (all samples) GSE34106: Gene expression profiling of archival tongue carcinoma and normal tongue tissue (subset) Refer to individual Series
ORGANISM(S): Homo sapiens 
2012-05-10 | E-GEOD-34115 | biostudies-arrayexpress
Sort   by:  
 Page size