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TranscriptomicsRNA-seq samples of ten tissues for B73 abnormal 10 (B73_Ab10)
These RNA-seq samples represent ten different tissue types for a version of the maize reference genome B73 with an abnormal chromosome 10 containing several knobs on the long arm involved in meiotic drive. This genome was sequenced by the NAM Consortium Group. These samples correspond to project ID ...
ORGANISM(S): Zea mays subsp. mays 
2020-04-23 | E-MTAB-8641 | biostudies-arrayexpress
TranscriptomicsRNA-seq of human epithelium-only colonic and small intestinal organoids derived from intestinal resections, biopsy specimens and cryopreserved crypts
Patient-derived gastrointestinal epithelium-only organoids from the small and large intestine, also referred to as colonoids and enteroids, were generated as part of the development of an on-going organoid biobank at the Michigan Medicine Translational Tissue Modeling Laboratory (TTML) (www.UmichTTM...
ORGANISM(S): Homo sapiens 
2020-07-24 | E-MTAB-9339 | biostudies-arrayexpress
GenomicsNkx2-1 Represses a Latent Gastric Differentiation Program in Lung Adenocarcinoma
Tissue-specific differentiation programs become dysregulated during cancer evolution. The transcription factor Nkx2-1 is a master regulator of pulmonary differentiation that is downregulated in poorly differentiated lung adenocarcinoma. Here we use conditional murine genetics to study the fate of l...
ORGANISM(S): Mus musculus 
2013-04-09 | E-GEOD-43252 | biostudies-arrayexpress
TranscriptomicsMelanoma-derived exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through upregulation of the MET oncoprotein.
Tumor-derived exosomes are emerging as mediators of tumorigenesis with a tissue-specific address and message. We explored the function of melanoma-derived exosomes in formation of primary tumors and metastatic progression in both murine models and patients. Whereas exosomes from highly metastatic me...
ORGANISM(S): Mus musculus 
2012-05-26 | E-GEOD-36584 | biostudies-arrayexpress
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