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TranscriptomicsEffects of aneuploidy on cellular physiology and cell division in haploid yeast.
Aneuploidy is a condition frequently found in tumor cells but how it affects cellular physiology is not known. We have characterized one aspect of aneuploidy, the gain of extra chromosomes. We created a collection of haploid yeast strains that each bear an extra copy of one or more of almost all of ...
ORGANISM(S): Saccharomyces cerevisiae 
2007-05-17 | E-GEOD-7812 | biostudies-arrayexpress
ProteomicsConsequences of aneuploidy in human fibroblasts
To characterize aneuploidy driven phenotypes in human trisomies, we performed global transcriptome, proteome, and phenotypic analysis of primary human fibroblasts from individuals with Patau (trisomy 13), Edwards (trisomy 18), or Down syndromes.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-09 | MSV000085706 | MassIVE
OtherQuantitative proteomic analysis reveals posttranslational responses to aneuploidy in yeast.
Data from ProteomeXchange, PXD ID: PXD001019. Experiment: Dis14, file: folder summary. Published as part of Elife. 2014 Jul 29:e03023 . From the Abstract: {{i}} Aneuploidy causes severe developmental defects and is a near universal feature of tumor cells. Despite its profound effects, the cellular ...
ORGANISM(S): Yeast 
GPM32320002303 | GPMDB
Resource Reanalysis 
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MetabolomicsHERPES SIMPLEX VIRUS TYPE 1 IMPAIRS DENDRITIC CELL FUNCTION BY REMODELLING NEUTRAL LIPID METABOLISM AND INDUCING LIPID DROPLET ACCUMULATION
Herpes simplex virus type 1 (HSV-1) infects dendritic cells (DCs), professional antigen-presenting cells that initiate and regulate host antiviral responses. HSV-1 infects DCs limiting their maturation, migration to draining lymph nodes and T cell activation capacity, ultimately promotes their apopt...
2025-04-03 | MTBLS5163 | MetaboLights
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S-EPMC11580631 | biostudies-literature
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UnknownThe first Miocene fossils from coastal woodlands in the southern East African Rift.
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S-EPMC10494320 | biostudies-literature
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