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TranscriptomicsOverexpression of the DNA-binding protein BIG1 (9619) in Thalassiosira pseudonana
Experimental evidence suggests that the novel conserved DNA-binding protein (BIG1) identified in Thalassiosira pseudonana and other centric diatoms increases resilience under harsh environmental settings, leading to a faster growth response upon return to more favorable growth conditions. To assess ...
ORGANISM(S): Thalassiosira pseudonana 
2024-08-31 | E-MTAB-14049 | biostudies-arrayexpress
TranscriptomicsRNA-seq transcriptome profiling of the psychrophilic phytoplankton Fragilariopsis cylindrus under environmentally relevant growth limitations
We performed RNA-sequencing experiments to examine the differential regulation of genes in the genome of the Southern Ocean diatom Fragilariopsis cylindrus including diverged alleles. RNA-seq was performed on three replicate samples for each experimental condition. Phytoplankton cells were grown und...
ORGANISM(S): Fragilariopsis cylindrus 
2016-12-16 | E-MTAB-5024 | biostudies-arrayexpress
TranscriptomicsTranscriptome Profiling of UCL93 Kidney Epithelial Cells and CRISPR-Cas9 Knockouts for PKD1 and BICC1 Using Total RNA-Seq
Autosomal Dominant Polycystic Kidney Disease (ADPKD) is the most common hereditary cause of kidney failure, resulting from germline mutations in PKD1 and PKD2 in over 90% of cases. Polycystin-1 (PC-1), a cell surface receptor linked to focal adhesion proteins, plays a critical role in regulating cel...
ORGANISM(S): Homo sapiens 
2026-07-27 | E-MTAB-14624 | biostudies-arrayexpress
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