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ProteomicsSubstrate Specificity of the TRAMP Nuclear Surveillance Complexes
During nuclear surveillance in yeast, the RNA exosome functions together with the TRAMP complexes. These include the DEAH-box RNA helicase Mtr4 together with an RNA-binding protein (Air1 or Air2) and a poly(A) polymerase (Trf4 or Trf5). To better determine how RNA substrates are targeted, we analyze...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2020-07-02 | PXD017114 | Pride
Trf4 Trf5 Nuclear surveillance Tramp complexes Rna-binding proteins 
TranscriptomicsRNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance
The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA helicase Mtr4, play a critical role in nuclear RNA surveillance. Although it is known to enhance the nuclease activity of ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | E-GEOD-42231 | biostudies-arrayexpress
GenomicsSubstrate Specificity of the TRAMP Nuclear Surveillance Complexes
Substrate Specificity of the TRAMP Nuclear Surveillance Complexes
PRJNA559170 | ENA
OtherSubstrate Specificity of the TRAMP Nuclear Surveillance Complexes
During nuclear surveillance, the RNA exosome functions together with the TRAMP complexes, which include the RNA helicase Mtr4 together with a RNA binding protein (Air1 or Air2) and a poly(A) polymerase (Trf4 or Trf5). To better determine how RNA substrates are targeted, we analyzed protein and RNA i...
ORGANISM(S): Saccharomyces cerevisiae 
2020-04-20 | GSE135526 | GEO
UnknownSubstrate specificity of the TRAMP nuclear surveillance complexes.
Not available
S-EPMC7305330 | biostudies-literature
UnknownNuclear RNA surveillance: role of TRAMP in controlling exosome specificity.
Not available
S-EPMC3578152 | biostudies-literature
TranscriptomicsRNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance
The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA helicase Mtr4, play a critical role in nuclear RNA surveillance. Although it is known to enhance the nuclease activity of ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | GSE42231 | GEO
UnknownThe RNA export and RNA decay complexes THO and TRAMP prevent transcription-replication conflicts, DNA breaks, and CAG repeat contractions.
Not available
S-EPMC9829180 | biostudies-literature
UnknownA genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection.
Not available
S-EPMC8893346 | biostudies-literature
UnknownN-Terminus of Cid14 Activates RNA Unwinding by Mtr4 in the <i>Schizosaccharomyces pombe</i> TRAMP Complex.
Not available
S-EPMC12577493 | biostudies-literature
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