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ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series: GSE16103: Wild-type versus trf4, trf5, and trf4-DADA mutant cells GSE16105: Trf4p in vivo crosslinking and ribonucleoprotein-immunopurification-chip analysis (X-RIP-Chip) Refer to individual Series
ORGANISM(S): Saccharomyces cerevisiae 
Measurement of the relative changes of gene expression of S. cerevisiae cells lacking either trf4 (trf4delta) or trf5 (trf5delta), and trf4delta/TRF4-DADA mutants compared to wild-type (WT) cells using yeast oligo microarrays that contain features representing all annotated yeast ORFs, ncRNAs, intro...
ORGANISM(S): Saccharomyces cerevisiae 
TRAMP is a eukaryotic protein complex with RNA helicase and polyadenylase activity that marks and delivers a variety of RNA substrates to the nuclear exosome for degradation. Prior work has characterized binding of Trf4 and Air2 to the helicase core of Mtr4 and the regulation of both enzymatic activ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-11 | PXD053773 | Pride
Drosophila Trf4-1 involvement in mRNA and primary miRNA transcription
In vivo cross-linking and ribonucleoprotein-immunopurification experiments followed by microarray analysis of bound RNAs (X-RIP-chip). Cells expressing recombinant tandem-affinity purification (TAP)-tagged Trf4 protein were cross-linked with formaldehyde, and Trf4-containing ribonucleoprotein comple...
ORGANISM(S): Saccharomyces cerevisiae 
Measurement of the relative changes of gene expression of S. cerevisiae cells lacking either trf4 (trf4delta) or trf5 (trf5delta), and trf4delta/TRF4-DADA mutants compared to wild-type (WT) cells using yeast oligo microarrays that contain features representing all annotated yeast ORFs, ncRNAs, intro...
ORGANISM(S): Saccharomyces cerevisiae 
2009-07-15 | GSE16103 | GEO
Drosophila Trf4-1 is a polyadenylation polymerase or terminal nucleotidyl transferase (PAP/TENT) that has been reported to add poly(A) tails to snRNAs in nucleus or mRNAs in cytoplasm. Here, we found that the loss of Trf4-1 resulted in the reduction of mRNAs and primary miRNAs (pri-miRNAs) in both D...
ORGANISM(S): Drosophila melanogaster 
2019-05-01 | GSE127210 | GEO
trf4, trf5, and trf4-DADA mutant cells gene expression Trf4p X-RIP-Chip
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