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MetabolomicsMetabolomics Linking Air Pollution, Obesity and Type 2 Diabetes
Not available
ORGANISM(S): Homo sapiens 
ST000909 | MetabolomicsWorkbench
ProteomicsHDX-MS of the TRAMP Complex with tRNA
TRAMP is a eukaryotic protein complex with RNA helicase and polyadenylase activity that marks and delivers a variety of RNA substrates to the nuclear exosome for degradation. Prior work has characterized binding of Trf4 and Air2 to the helicase core of Mtr4 and the regulation of both enzymatic activ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2024-12-11 | PXD053773 | Pride
Hdx Trf4 Tramp Air2 Rna Hdx-ms Mtr4 
UnknownTRAMP assembly alters the conformation and RNA binding of Mtr4 and Trf4-Air2.
Not available
S-EPMC11725892 | biostudies-literature
UnknownRNA unwinding by the Trf4/Air2/Mtr4 polyadenylation (TRAMP) complex.
Not available
S-EPMC3358879 | biostudies-literature
TranscriptomicsRNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance
The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA helicase Mtr4, play a critical role in nuclear RNA surveillance. Although it is known to enhance the nuclease activity of ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | E-GEOD-42231 | biostudies-arrayexpress
TranscriptomicsRNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance
The Saccharomyces cerevisiae TRAMP4 and TRAMP5 complexes, which consist of the poly(A) polymerase Trf4 or Trf5, respectively, the zinc knuckle proteins Air1 or Air2, and the RNA helicase Mtr4, play a critical role in nuclear RNA surveillance. Although it is known to enhance the nuclease activity of ...
ORGANISM(S): Saccharomyces cerevisiae 
2012-11-14 | GSE42231 | GEO
GenomicsSaccharomyces cerevisiae
RNA-seq reveals that Air1 and Air2 control TRAMP substrate specificity for nuclear RNA surveillance
PRJNA179372 | ENA
UnknownLong-term outcomes of bronchial thermoplasty in subjects with severe asthma: a comparison of 3-year follow-up results from two prospective multicentre studies.
Not available
S-EPMC5593347 | biostudies-literature
UnknownGenome-Scale Profiling and High-Throughput Analyses Unravel the Genetic Basis of Arsenic Content Variation in Rice.
Not available
S-EPMC9361212 | biostudies-literature
UnknownStructural analysis reveals the characteristic features of Mtr4, a DExH helicase involved in nuclear RNA processing and surveillance.
Not available
S-EPMC2901443 | biostudies-literature
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