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ProteomicsTransgelin silencing induces different processes in differrent breast cancer cell lines
Transgelin is a protein which has been described as a marker of several cancers. Interestingly, the literature describes both up- and down-regulation of transgelin in the tumor in comparison with non-tumor tissue. The mechanisms of transgelin function in cancer are considerably unknown. Transgelin i...
ORGANISM(S): Homo sapiens (Human) 
2020-02-21 | PXD016316 | Pride
Transgelin  breast cancer  metastasis  migration  apoptosis  cytoskeleton 
ProteomicsTransgelin contributes to a poor response of metastatic renal cell carcinoma to sunitinib treatment
Renal cell carcinoma (RCC) represents about 2-3% of all cancers with over 400,000 new cases per year. Sunitinib, a vascular endothelial growth factor tyrosine kinase receptor inhibitor, has been used mainly for first-line treatment of metastatic clear-cell RCC with good or intermediate prognosis. Ho...
ORGANISM(S): Homo sapiens (Human) 
2021-11-03 | PXD027065 | Pride
Mccrcc  sunitinib  resistance  dia-ms  transgelin 
GenomicsGene expression analysis of Subperitoneal Fibroblast (SPF) by knockdown of Transgelin.
Gene expression analysis of Subperitoneal Fibroblast (SPF) by knockdown of Transgelin.
PRJNA1185306 | ENA
ProteomicsQuantitative proteomics reveals that distant recurrence-associated protein R-Ras and Transgelin predict post-surgical survival of colorectal cancer Stage III patients
Surgical resection is the major clinical intervention for Stage III colorectal cancer (CRC) currently. However, as much as 30.8% of the patients who had ever taken curative resection came out of recurrence eventually. Therefore, to facilitate formulating effective treatment plans, there is an intens...
ORGANISM(S): Homo sapiens (Human) 
2016-06-20 | PXD002903 | Pride
Transgelin. Stage iii colorectal cancer Prognostic biomarker Post-surgical recurrence R-ras Quantitative proteomics 
TranscriptomicsGene expression analysis of Subperitoneal Fibroblast (SPF) by knockdown of Transgelin.
Transgelin expression in colorectal cancer has been reported to correlate with patient prognosis. The aim of this study was to investigate the function of Transgelin in fibroblasts of colorectal cancer. As a method, we assessed whether knockdown of Transgelin alters the expression of the gene.
ORGANISM(S): Homo sapiens 
2026-04-13 | GSE281727 | GEO
UnknownTransgelin Up-Regulation in Obstructive Nephropathy.
Not available
S-EPMC3694161 | biostudies-literature
UnknownEvolution and function of calponin and transgelin.
Not available
S-EPMC10285543 | biostudies-literature
UnknownTransgelin interacts with PARP1 in human colon cancer cells.
Not available
S-EPMC7398379 | biostudies-literature
UnknownTransgelin-2: Biochemical and Clinical Implications in Cancer and Asthma.
Not available
S-EPMC7023894 | biostudies-literature
GenomicsTransgelin 2 guards T cell lipid metabolism and anti-tumor function
Transgelin 2 guards T cell lipid metabolism and anti-tumor function
PRJNA1044826 | ENA
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