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TranscriptomicsExpression profile of adult Drosophila melanogaster expressing a self-replicating RNA of Sindbis virus
Alphaviruses establish a persistent infection in arthropod vectors, which is essential for effective transmission of the virus to vertebrate hosts. The development of persistence in insects is not well understood, although it is thought to involve the innate immune response. Using a transgenic fly s...
ORGANISM(S): Drosophila melanogaster 
2013-01-31 | E-GEOD-42726 | biostudies-arrayexpress
GenomicsSex comb on midleg (Scm) is a functional link between PcG repressive complexes in Drosophila
We profiled Sex comb on midleg (Scm), Pc and E(z) in fly embryos and S2 based on BioTAP-XL ChIP-seq. ChIP-seq revealed that Scm is co-localized with PRC1, PRC2, and H3K27me3 in both S2 cells and embryos. Genomic binding/occupancy profiling of Scm, Pc and E(z) by high throughput sequencing
ORGANISM(S): Drosophila melanogaster 
2015-07-09 | E-GEOD-66183 | biostudies-arrayexpress
GenomicsA strand-specific switch in noncoding transcription switches the function of a Polycomb/Trithorax response element
Polycomb/Trithorax response elements (PRE/TREs) can switch their function reversibly between silencing and activation, by mechanisms that are poorly understood. Here we show that a switch in forward and reverse noncoding transcription from the Drosophila vestigial (vg) PRE/TRE switches the status of...
ORGANISM(S): Drosophila melanogaster 
2014-08-10 | E-GEOD-59192 | biostudies-arrayexpress
UnknownThe Transgenic RNAi Project at Harvard Medical School: Resources and Validation.
Not available
S-EPMC4649654 | biostudies-literature
UnknownFly-Tox: A panel of transgenic flies expressing pest and pollinator cytochrome P450s.
Not available
S-EPMC7482442 | biostudies-literature
TranscriptomicsExpression profiling of over-expression of conspecific and heterspecific miR-310 cluster in Drosophila (tiling array)
The miRNA 310-311-312-313 cluster from D. melanogaster (referred to as Dm310s) and the homolog from D. pseudoobscura (Dp310s) were used to transform D. melanogaster. The over-expression of UAS-miR310s in two Dm310s transgenic lines (M1-7 and M1-3) and Dp310s transgenic line P4-18 was driven by GAL4 ...
ORGANISM(S): Drosophila melanogaster 
2010-06-24 | E-GEOD-15850 | biostudies-arrayexpress
TranscriptomicsDrosophila melanogaster 4C-Seq experiments in wild-type and ectopic E3 enhancer-inserted embryos
Chromosome conformation capture (4C-Seq) in Drosophila embryos from a wild-type line and from transgenic fly lines carrying the E3 enhancer of twist at ectopic locations. Two time points (2-5 hrs and 5-8 hrs after egg lay) and two viewpoints located near the twist promoter were assayed. Two independ...
ORGANISM(S): Drosophila melanogaster 
2023-12-08 | E-MTAB-12153 | biostudies-arrayexpress
UnknownEstablishment of transgenic lines to monitor and manipulate Yap/Taz-Tead activity in zebrafish reveals both evolutionarily conserved and divergent functions of the Hippo pathway.
Not available
S-EPMC4138299 | biostudies-literature
UnknownImprovement on the genetic engineering of an invasive agricultural pest insect, the cherry vinegar fly, Drosophila suzukii.
Not available
S-EPMC7747376 | biostudies-literature
UnknownDrosophila pVALIUM10 TRiP RNAi lines cause undesired silencing of Gateway-based transgenes.
Not available
S-EPMC9711858 | biostudies-literature
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