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MetabolomicsPrimary Osteocyte Supernatants Metabolomic Profiling of Two Transgenic Mice with Connexin43 Dominant Negative Mutants

Osteocytes could release some small molecules (≤ 1 kDa) through gap junctions and hemichannels to extracellular environment, such as prostaglandin E2 (PGE2), nitric oxide (NO) and adenosine triphosphate (ATP), which play key roles in transferring signals between bone cells and other tissue cells....

2021-04-14 | MTBLS2358 | MetaboLights
MetabolomicsLipidome Signatures of Metastasis in a Transgenic Mouse Model of Sonic Hedgehog Medulloblastoma.
Not available
ORGANISM(S): Mus musculus 
ST001290 | MetabolomicsWorkbench
UnknownA transgenic mouse line for assaying tissue-specific changes in endoplasmic reticulum proteostasis.
Not available
S-EPMC10195735 | biostudies-literature
ProteomicsComprehensive N-glycoproteomic profiling of humanized antibody expressed in transgenic mouse serum
This dataset reports a comprehensive N-glycoproteomic profiling of serum-derived humanized antibodies expressed in transgenic mice using an intact glycopeptide (IGP)–based LC–MS/MS workflow. The study aimed to identify and characterize site-specific N-glycosylation modifications of mouse serum prote...
ORGANISM(S): Mus musculus (Mouse) 
2025-12-08 | PXD070488 | Pride
Antibody Transgenic mouse Post-translational modification Glycoproteomics Orbitrap astral N-glycosylation Intact glycopeptides Dda Lc–ms/ms 
TranscriptomicscaArray_green-00155: Global expression profiling identifies signatures of tumor virulence in MMTV-PyMT-transgenic mice
Comparison the gene expression profiles of mouse mammary tumors derived from MMTV-PyMT transgenic in five different strains including FVB/NJ, I/LnJ F1, NZB/B1NJ F1, MOLF/Ei F1 and LP/J F1 and identification of signatures of tumor virulence. **NOTE: Migrated from caArray 1.x, identifier='gov.nih.nci....
ORGANISM(S): Mus musculus 
2015-06-20 | E-GEOD-70052 | biostudies-arrayexpress
ProteomicsHuman SMARCA5 interactome in transgenic SMARCA5 mouse model
We hypothesize that the ISWI ATPase Smarca5 plays a role in hematopoietic stem cell development via its interaction partners, and to study the role, we used a mouse model with transgenic expression of SMARCA5 coupled with mass spectrometry analysis. The study uses transgenic SMARCA5 mouse model with...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-22 | PXD049034 | Pride
Smarca5 Transgenic mice Immunoprecipitation 
TranscriptomicsMolecular and phenotypic characterization of a mouse model of oculopharyngeal muscular dystrophy reveals severe muscular atrophy restricted to fast glycolytic fibres
Oculopharyngeal muscular dystrophy (OPMD) is an adult-onset disorder characterized by ptosis, dysphagia and proximal limb weakness. Autosomal-dominant OPMD is caused by a short (GCG)8–13 expansions within the first exon of the poly(A)-binding protein nuclear 1 gene (PABPN1), leading to an expanded p...
ORGANISM(S): Mus musculus 
2011-01-14 | E-GEOD-26604 | biostudies-arrayexpress
TranscriptomicsCardiac Gene Expression Profiling in CryAB R120G Transgenic Mice
Protein aggregation cardiomyopathy is a life-threatening manifestation of a multisystem disorder caused by the exchange mutation in the gene encoding the human small HSP ?B-crystallin (hR120GCryAB). Genetic studies in mice have established cardiac hR120GCryAB expression causes increased activity of...
ORGANISM(S): Mus musculus 
2008-12-12 | E-GEOD-9924 | biostudies-arrayexpress
TranscriptomicsMedulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse allografted in nude mice
Nude mice were allografted with medulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse and treated with vehicle or NVP-LDE225. RNA was prepared from tumours from vehicle or NVP-LDE225 treated nude mice allografted with medulloblastoma tumors derived from Ptch+/-HIC+/- transgenic mouse an...
ORGANISM(S): Mus musculus 
2010-09-29 | E-GEOD-22005 | biostudies-arrayexpress
ProteomicsProteome analysis of transgenic 1D1a mice
T cells specifically recognize an antigen with a T cell receptor (TCR) consisting of α- and β-chain. The transgenic 1D1a mice were generated on the genetic background of the B10.D2(R101) line and expressed in their T cells the α-chain TCR (TCRα) specific to the allogeneic MHC molecule Н2-Kb. To eval...
ORGANISM(S): Mus musculus (Mouse) 
2023-05-10 | PXD034188 | Pride
Lc-msms Blood plasma Transgenic 1d1a mice 
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