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ProteomicsAgonists of orally expressed TRP channels stimulate salivary secretion and modify the salivary proteome
Natural compounds that can stimulate salivary secretion are of interest in developing treatments for xerostomia, the perception of a dry mouth, that affects between 10 and 30% of the adult and elderly population. Chemesthetic transient receptor potential (TRP) channels are expressed in the surface ...
ORGANISM(S): Homo sapiens (Human) 
2020-07-16 | PXD017232 | Pride
Menthol Proteome Transient receptor potential channel agonists Nonivamide Saliva Cinnamaldehyde 
GenomicsN-Palmitoylglycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome
N-Palmitoylglycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome
PRJNA1167235 | ENA
UnknownActivation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.
Not available
S-EPMC4371942 | biostudies-literature
TranscriptomicsN-Palmitoylglycine activates transient receptor potential channel 5 and increases the risk of Brugada syndrome
Brugada syndrome (BrS) is an arrhythmic disorder associated with an increased risk of sudden cardiac death; however, current treatment options are limited due to their side effects and variable efficacy. In this study, we employed Mendelian randomization analysis utilizing proteomic, transcriptomic,...
ORGANISM(S): Rattus norvegicus 
2024-10-05 | GSE278421 | GEO
UnknownTransient receptor potential melastatin 3 is a phosphoinositide-dependent ion channel.
Not available
S-EPMC4485020 | biostudies-literature
UnknownEnglerin A-sensing charged residues for transient receptor potential canonical 5 channel activation.
Not available
S-EPMC6488704 | biostudies-literature
UnknownVitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel.
Not available
S-EPMC7589233 | biostudies-literature
UnknownStructural determinants of the transient receptor potential 1 (TRPV1) channel activation by phospholipid analogs.
Not available
S-EPMC4148841 | biostudies-literature
UnknownEpisodic pain in Fabry disease is mediated by a heat shock protein-transient receptor potential cation channel A1 axis.
Not available
S-EPMC12527330 | biostudies-literature
UnknownTransient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation.
Not available
S-EPMC2689921 | biostudies-literature
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