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ProteomicsHDX-MS of TRAPPII reveals a conserved Rab binding interface
We used hydrogen deuterium exchange mass spectrometry (HDX-MS) to define the interface of TRAPPII with three Rab GTPases (Rab1, Rab11, Rab43). These experiments were performed in the presence of EDTA to generate a nucleotide free stabilised Rab-GEF complex. Significant decreases in deuterium incorpo...
ORGANISM(S): Homo sapiens (Human) 
2020-12-11 | PXD020890 | Pride
Hdx-ms Trappii Gef Rab 
ProteomicsStudy of the TRAPP complexes by HDX-MS
Use of HDX-MS to study the allosteric and structural differences between the TRAPPII and TRAPPIII complex in the presence and absence of membrane and rab GTPases
ORGANISM(S): Homo sapiens (Human) 
2021-09-22 | PXD025928 | Pride
Trappii trappiii rab hdx-ms 
UnknownMolecular architecture of the TRAPPII complex and implications for vesicle tethering.
Not available
S-EPMC2988884 | biostudies-literature
UnknownStructure of a TRAPPII-Rab11 activation intermediate reveals GTPase substrate selection mechanisms.
Not available
S-EPMC9106297 | biostudies-literature
UnknownThe substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity.
Not available
S-EPMC7719173 | biostudies-literature
UnknownTRAPPII regulates exocytic Golgi exit by mediating nucleotide exchange on the Ypt31 ortholog RabERAB11.
Not available
S-EPMC4394270 | biostudies-literature
UnknownStructural basis for assembly of TRAPPII complex and specific activation of GTPase Ypt31/32.
Not available
S-EPMC8791620 | biostudies-literature
ProteomicsInteractions between Transport Protein Particle (TRAPP) complexes and Rab GTPases in Arabidopsis
The Transport Protein Particle II (TRAPPII) is essential for exocytosis, endocytosis, protein sorting and cytokinesis. In spite of a considerable understanding of its biological role, little is known about Arabidopsis TRAPPII complex topology and molecular function. In this study, independent proteo...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2019-09-03 | PXD013016 | Pride
Trappii Arabidopsis Co-ip Protein complex Rab gtpases Transport protein particle 
UnknownRegulation of adaptive growth decisions via phosphorylation of the TRAPPII complex in Arabidopsis.
Not available
S-EPMC10983811 | biostudies-literature
UnknownCharacterization of Aspergillus nidulans TRAPPs uncovers unprecedented similarities between fungi and metazoans and reveals the modular assembly of TRAPPII.
Not available
S-EPMC6946167 | biostudies-literature
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