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ProteomicsThe proteomic response of C. elegans to two protective Pseudomonas symbionts
The two C. elegans natural microbiota isolates Pseudomonas lurida MYb11 and Pseudomonas fluorescens MYb115 protect the host against pathogens through distinct mechanisms. While P. lurida produces an antimicrobial compound and directly inhibits pathogen growth, P. fluorescens MYb115 protects the host...
ORGANISM(S): Caenorhabditis elegans 
2024-05-24 | PXD040520 | Pride
C. elegans Microbiota Host-symbiont interactions 
ProteomicsThe C. elegans proteome response to alternative food source bacteria
Understanding how C. elegans interacts with the bacteria it feeds upon enables us to better comprehend the complex interactions occurring at the interface of host and microbe. Here we have assessed the proteome of C. elegans after growth on bacteria capable of colonising the gut via a comparative an...
ORGANISM(S): Caenorhabditis elegans 
2018-03-13 | PXD008105 | Pride
Caenorhabditis elegans 2d lc-msms Isobaric labelling 
UnknownThe Caenorhabditis elegans proteome response to two protective Pseudomonas symbionts.
Not available
S-EPMC11005407 | biostudies-literature
UnknownThe mitochondrial BCKD complex interacts with hepatic apolipoprotein E in cultured cells in vitro and mouse livers in vivo.
Not available
S-EPMC9905200 | biostudies-literature
UnknownHost modification of a bacterial quorum-sensing signal induces a phenotypic switch in bacterial symbionts.
Not available
S-EPMC5635886 | biostudies-literature
UnknownEnzyme-fusion strategies for redirecting and improving carotenoid synthesis in S. cerevisiae.
Not available
S-EPMC6350077 | biostudies-literature
UnknownCombining systems and synthetic biology for in vivo enzymology.
Not available
S-EPMC11535393 | biostudies-literature
ProteomicsIntracellular proteome response of the gut bacterium Bacteroides thetaiotaomicron to the metabolic switch from glucose to sucrose as the sole carbon source
Bacteroides thetaiotaomicron (B. thetaiotaomicron) is an essential bacterial representative of the human gut microbiome that metabolizes a wide range of dietary and mucosal polysaccharides. Here, we analyze the intracellular proteomic response of in vitro grown B. thetaiotaomicron to the metabolic s...
ORGANISM(S): Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / NCTC 10582 / E50 / VPI-5482) 
2022-10-15 | PXD033704 | Pride
Label free quantifications Isobaric labeling Ibd Inflammation Tmt Carbohydrate metabolism Bottom up Lfq Bacterial proteomics High/low ph 2d-lc 
ProteomicsThe hepatic BCKD complex interacts with apolipoprotein E in vivo and its enzyme activity is increased in APOE4 mice
APOE co-immunoprecipitation (co-IP) in liver of APOE targeted replaecement mice followed by LC−MS was used to analyse APOE protein−protein interactions and to detect as yet unknown interactor proteins.
ORGANISM(S): Mus musculus (Mouse) 
2023-03-10 | PXD033961 | Pride
Apoe  co-immunoprecipitation 
ProteomicsA mitochondrial sirtuin shapes the intestinal microbiota by controlling lysozyme expression
Sirtuins are sensors that orchestrate cellular responses to adapt to changing situations. Here, we show that a protein-restricted diet induces strongly induces increased intestinal expression of the sole Drosophila mitochondrial sirtuin, dSirt4. To elucidate the effects of deregulated dSirt4 express...
ORGANISM(S): Drosophila melanogaster (Fruit fly) 
2025-06-23 | PXD054704 | Pride
Drosophila  lc-ms  sirtuin-4 
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