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ProteomicsProtein EV contents from C. elegans
The hermaphrodite strain N2 (Bristol), fed with Escherichia coli OP50, was maintained and synchronized. Young adults were thoroughly washed before incubations for 5 h or 24 h in M9 buffer. Between 35,500 and 158,000 worms were used for each experiment. After incuabtion, supernatants were processed b...
ORGANISM(S): Escherichia coli Caenorhabditis elegans 
2020-05-04 | PXD017352 | Pride
Extracellular vesicles Lc-ms Caenorhabditis elegans 
TranscriptomicsCirculating Dirofilaria immitis microRNAs in dog plasma
We report the presence of circulating miRNAs released by the filarial nematode Dirofilaria immitis into the host (Canis familiaris) bloodstream. MiRNA deep-sequencing combined with bioinformatics revealed over 200 mature miRNA sequences of potential nematode origin in Dirofilaria immitis-infected do...
ORGANISM(S): Canis lupus familiaris 
2014-10-03 | E-GEOD-60170 | biostudies-arrayexpress
ProteomicsQuantitative proteomics analysis of Angiostrongylus vasorum-induced alterations in dog serum
Blood contains hundreds of proteins, reflecting ongoing cellular processes and immune reactions. Angiostrongylus vasorum infection is associated with a perturbed blood protein profile in dogs. However, the literature currently available lacks the necessary depth of analysis in order to resolve the o...
ORGANISM(S): Canis Lupus Familiaris 
2021-01-24 | PXD016887 | panorama
TranscriptomicsDeciphering the loss of fertility in ivermectin-treated Brugia malayi females in vitro: a transcriptomic approach [Study I]
In this study, we analyzed transcriptomic profiles from ivermectin-treated and -untreated B. malayi adult females using Next Generation RNA Sequencing technology at different concentrations (100 nM, 300 nM and 1 µM) and time points (24, 48, 72 h, and 5 days). Our analysis revealed altered expressio...
ORGANISM(S): Brugia malayi 
2016-07-27 | E-GEOD-75339 | biostudies-arrayexpress
TranscriptomicsDeciphering the loss of fertility in ivermectin-treated Brugia malayi females in vitro: a transcriptomic approach [Study II]
In this study, we analyzed transcriptomic profiles from ivermectin-treated and -untreated B. malayi adult females using Next Generation RNA Sequencing technology at different concentrations (100 nM, 300 nM and 1 µM) and time points (24, 48, 72 h, and 5 days). Our analysis revealed altered expressio...
ORGANISM(S): Brugia malayi 
2016-07-27 | E-GEOD-75340 | biostudies-arrayexpress
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